Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe +2 more
wiley +1 more source
Measuring adult mortality from mobile phone surveys in Burkina Faso, Malawi and the Democratic Republic of the Congo. [PDF]
Dianou K +10 more
europepmc +1 more source
Can Flash Flood Risk Index Be an Early Warning Signal of Flash Floods in Ungauged Basin?
ABSTRACT Flash flooding is amongst the most severe natural hazards, causing widespread socioeconomic impacts across both wet regions and drylands. In ungauged mountainous basins, effective risk warning based on hydrodynamic modelling is challenging due to sparse hydrological observations and complex terrain.
Kaihua Guo, Mingfu Guan, Jie Yin
wiley +1 more source
Seven Strategies Implemented in Response to the 16th Ebola Virus Disease Outbreak in the Democratic Republic of Congo: Lessons Learned over a Three-Month Period. [PDF]
Mwamba DK +31 more
europepmc +1 more source
Evaluating the Genetic Overlap Between Congenital Heart Disease and Neuroblastoma Risk
ABSTRACT Children with congenital heart disease (CHD) have elevated neuroblastoma (NB) risk, potentially due to shared neural crest origins. We analyzed rare exonic de novo single‐nucleotide variants in 702 CHD and 454 NB trios from the Neuroblastoma Epidemiology in North America Study, Gabriella Miller Kids First Program, and a published cohort. Seven
Ji Yun Tark +7 more
wiley +1 more source
The 2024-2025 upsurge of mpox in Africa: another opportunity to accelerate global solidarity for a neglected disease. [PDF]
Onyeaghala C, Iroezindu M.
europepmc +1 more source
Aims Resistance to the artemisinins and the artemisinin‐based combination therapy (ACT) partner drugs has developed in Southeast Asia, and artemisinin resistance has also emerged in eastern Africa. Triple ACTs (triple artemisinin‐based combination therapies, TACT), consisting of two partner drugs with different mechanisms of action and similar ...
Junjie Ding +24 more
wiley +1 more source
Links between infrastructure for human movement and early Ebola outbreak trajectories. [PDF]
Gonzalez A +7 more
europepmc +1 more source
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo +22 more
wiley +1 more source
Peritoneal dialysis influences microRNA expression and pro-inflammatory response: results from a cross-sectional study. [PDF]
Costa NA +14 more
europepmc +1 more source

