Results 31 to 40 of about 28,329 (218)

Incidence, severity and distribution of Cassava brown streak disease in northeastern Democratic Republic of Congo

Cogent Food & Agriculture, 2020
Cassava fields were prospected from two provinces of the Democratic Republic of Congo (Ituri and Haut Uélé) to evaluate the ampleness of Cassava brown streak disease (CBSD) infection.
Honoré Muhindo, Sabrine Yasenge, Clérisse Casinga, Médard Songbo, Benoît Dhed’a, Titus Alicai, Justin Pita, Godefroid Monde   +7 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

An End-to-End NLP Pipeline Combining Web Scraping, CamemBERT Fine-Tuning and Zero-Shot Biomedical Named-Entity Recognition for Early Epidemic Signal Detection from French-Language Online News

Journal of Applied Informatics and Computing
Epidemiological surveillance in the Democratic Republic of the Congo (DRC) suffers from reporting delays and limited digital infrastructure, while online French-language news provides a complementary real-time signal that current systems exploit poorly ...
Franklin Mwamba, Fiston Oshasha, Saint Jean Djungu, John Poma   +3 more
doaj   +1 more source

Self‐Amplified Activatable Fluorescent Probe for Early Diagnosis of Acute Kidney Injury and High‐Throughput Screening of Natural Protectants

Advanced Science, EarlyView.
The PS‐QRC nanoprobe employs L‐serine as a targeting ligand for kidney injury molecule‐1 (KIM‐1) to achieve accumulation in injured renal tissues. Upon activation by reactive oxygen species (ROS), it undergoes a self‐amplifying cascade to release fluorophores for near‐infrared fluorescence (NIRF) imaging, enabling ultra‐early diagnosis of acute kidney ...
Yahui Chen, Meihong Liu, Mengchao Ding, Ye Liu, Chuanxu Zhu, Mingye Gong, Zhixuan Huang, Yi Zhang, Wei Xue, Youyong Yuan, Kewei Wang   +10 more
wiley   +1 more source

A Generalizable Framework for Building Executable Domain‐Specific Large Language Models Under Data Scarcity: Demonstration on Semiconductor Technology Computer‐Aided Design Simulation

Advanced Intelligent Systems, EarlyView.
A schema‐first alignment framework builds compact, executable domain‐specific language models under data scarcity. Large‐scale synthetic question‐answer generation instills domain knowledge, and a code‐centric IR‐to‐DPO pipeline aligns generation with tool‐executable syntax.
Di Wang, Zhenhua Wu, Yu Liu, Kai Chang, Shaohua Wu   +4 more
wiley   +1 more source

Exposure to heat waves and drought improves subsequent leaf heat tolerance for five oak species in southern California

American Journal of Botany, EarlyView.
Abstract Premise Given the threats of climate change, we investigated the impact of high temperatures separately and in combination with reduced soil water on leaf heat tolerance for five oaks (Fagaceae) with overlapping ranges in southern California, USA: Quercus agrifolia and Q. chrysolepis (evergreen species), Q. douglasii and Q.
Casey D. Wisely, G. Olivia Plumb, Mira N. Ranganath, Emily Dolida, Ishan Ashford, Graham Luethe, Tim Thibault, Gretchen B. North   +7 more
wiley   +1 more source

Challenges to COVID-19 vaccine introduction in the Democratic Republic of the Congo – a commentary

Human Vaccines & Immunotherapeutics, 2022
COVID-19 vaccination in the Democratic Republic of the Congo (DRC) began in April 2021. A month later, most COVID-19 vaccine doses were reallocated to other African countries, due to low vaccine uptake and the realization that the doses would expire ...
Trésor Zola Matuvanga, Reena H. Doshi, Albert Muya, Aimé Cikomola, Augustin Milabyo, Pablito Nasaka, Patrick Mitashi, Hypolite Muhindo-Mavoko, Steve Ahuka, Michel Nzaji, Nicole A. Hoff, Robert Perry, Elisabeth Mukamba Musenga   +12 more
doaj   +1 more source

‘Who Can Sing the Song of MSF?’ The Politics of ‘Proximity’ and Performing Humanitarianism in Eastern DRC

Journal of Humanitarian Affairs, 2020
This article explores the everyday practice of security management and negotiations for access conducted by Médecins Sans Frontières (MSF) in North Kivu, in the Democratic Republic of the Congo (DRC).
Myfanwy James
doaj   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Producing Journalistic Discourse on War: A Congolese Experience

Journal of Humanitarian Affairs, 2020
Based on the author’s experience as both a journalist and an independent researcher working regularly in eastern Democratic Republic of Congo (DRC), this article examines the many constraints that journalists face in areas of armed conflict. It considers
Justine Brabant
doaj   +1 more source