Results 131 to 140 of about 2,631,684 (301)

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Bioanalysis of Small Molecule Pharmaceuticals: Simultaneous Determination in Biological Fluid Samples from Multiple Species by the Management of Matrix Effects [PDF]

A strategy is described for method evaluation to manage the influence of endogenous compounds to induce bias in pharmaceutical quantification from blood samples of different animal species resulting from ionisation matrix effects. The approach introduces
Gray, Nicholas
core  

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Wearable Morphology‐Adaptive in‐Ear Device With Active Cleansing Capability for Multimodal Health Monitoring

Advanced Materials, EarlyView.
We present SCIENCE, an in‐ear multimodal physiological monitor featuring two key innovations. Water‐triggered morphological expansion (a 2‐mm cylinder to a 9‐mm spindle) achieves conformal adaptation across complex canal geometries. Simultaneously, active biofouling mitigation disrupts cerumen barriers, reducing sensor‐skin impedance by 20%.
Shuyun Zhuo, Zihuan Wu, Anan Zhang, Shideh Kabiri Ameri   +3 more
wiley   +1 more source

Electropolymerized Aptasensor for Femtogram‐Level Cytokine Detection

Advanced Materials, EarlyView.
Electropolymerization of 3‐amino‐ʟ‐tyrosine creates ultrathin, smooth, and chemically robust pALT nanofilms with accessible carboxyl functionalities for direct aptamer immobilization. Integrated with fiber‐optic SPR and OECT platforms, these interfaces enable IL‐6 detection down to 100 fg mL−1 and provide a versatile route to bioelectronic sensing ...
Jiyao Yu, Renan Colucci, Rachel X. Shi, Qi Lu, Tommaso Marchesi D'Alvise, Ulrike Kraft, Christopher V. Synatschke, Tanja Weil   +7 more
wiley   +1 more source

Positive Infant Dried Blood Spot PCR by Year for Arusha, Kilimanjaro, Tanga Regions.

, 2014
Positive Infant Dried Blood Spot PCR by Year for Arusha, Kilimanjaro, Tanga Regions.
Sheng Feng (194527), Dorothy E. Dow (522696), John A. Bartlett (231233), Balthazar Nyombi (496112), Aisa Shayo (522698), Coleen K. Cunningham (522700), Charles G. Massambu (522697), Werner Schimana (522701), Ann M. Buchanan (522695), Rahma Musoke (522699)   +9 more
core   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

Advanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian, Xu Wang, Alexis Pacheco Benitez, Erick Guerrero, Yaou Duan, Jingwen Wei, Lukas Farbiak, Daniel J. Siegwart   +7 more
wiley   +1 more source

Advantages and challenges of dried blood spot analysis by mass spectrometry across the total testing process

, 2016
Introduction Through the introduction of advanced analytical techniques and improved throughput, the scope of dried blood spot testing utilising mass spectrometric methods, has broadly expanded.
Jennifer Koplin (3919724), Katrina Allen (13591012), Ronda Greaves (18044008), Rosita Zakariaee Abkoo (18026209), Peter Roche (20006109)   +4 more
core  

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

Rapid detection of urinary tract infection by analyzing the dried spots of biological fluids using convolutional neural networks

Scientific Reports
To find the cause of infectious diseases such as urinary tract infections, a the diagnostic patterning test was used. In this method, the whole blood and serum samples for every person were dried on a glass substrate to create a special pattern due to ...
Mohammad Mahdi Bordbar, Fatemeh Nobakht M. Gh., Azarmidokht Sheini, Maryam Alborz, Raheleh Halabian, Afsaneh Pargar, Hosein Khoshsafar, Gözde Baydemir, Hosein Samadinia, Hasan Bagheri   +9 more
doaj   +1 more source