Results 61 to 70 of about 738,625 (360)

Detection of Calibration Drift in Clinical Prediction Models to Inform Model Updating

open access: yesJournal of Biomedical Informatics, 2020
Model calibration, critical to the success and safety of clinical prediction models, deteriorates over time in response to the dynamic nature of clinical environments.
Sharon E. Davis   +4 more
semanticscholar   +1 more source

A Systematic Study of Online Class Imbalance Learning With Concept Drift [PDF]

open access: yesIEEE Transactions on Neural Networks and Learning Systems, 2017
As an emerging research topic, online class imbalance learning often combines the challenges of both class imbalance and concept drift. It deals with data streams having very skewed class distributions, where concept drift may occur.
Shuo Wang, Leandro L. Minku, X. Yao
semanticscholar   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Stochastic Evolutionary Dynamics: Drift vs. Draft [PDF]

open access: yes, 2004
In a small handful of papers in theoretical population genetics, John Gillespie argues that a new stochastic process he calls "genetic draft" is evolutionarily more significant than genetic drift. This case study of chance in evolution explores Gillespie'
Skipper, Robert
core  

Blaťácké Zlato Cheese: A Screenshot of Its Biofunctional and Physicochemical Characteristics

open access: yesFoods
This study aims to determine the Blaťácké zlato cheese in vitro antioxidant activity and its correlation with specific peptides. A general physicochemical evaluation was also conducted, considering possible differences between batches.
Sandra T. Martín-del-Campo   +6 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Concepts of Drift and Selection in “The Great Snail Debate” of the 1950s and Early 1960s [PDF]

open access: yes, 2007
Recently, much philosophical discussion has centered on the best way to characterize the concepts of random drift and natural selection, and, in particular, on the question of whether selection and drift can be conceptually distinguished (Beatty 1984 ...
Millstein, Roberta L.
core  

The Overnight Drift

open access: yesSSRN Electronic Journal, 2020
Abstract This paper documents that U.S. equity returns are large and positive during the opening hours of European markets. These returns are pervasive and highly economically and statistically significant. Consistent with models of inventory risk, we demonstrate a strong relationship with order imbalances at the close of the preceding U.
Boyarchenko, Nina   +2 more
openaire   +6 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Are Random Drift and Natural Selection Conceptually Distinct? [PDF]

open access: yes, 2001
The latter half of the twentieth century has been marked by debates in evolutionary biology over the relative significance of natural selection and random drift: the so-called neutralist/selectionist debates.
Millstein, Roberta L.
core  

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