Results 41 to 50 of about 617,554 (343)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

open access: yesMolecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker   +3 more
wiley   +1 more source

Preliminary Investigation into Measurement While Drilling as a Means to Characterize the Coalmine Roof

open access: yesResources, 2020
The variable nature of the coalmine roof poses a challenge to roadway stability during underground coal mining. There have been fatalities and financial losses in the coal mining industry due to roadway failures and roof falls.
Manoj Khanal   +3 more
doaj   +1 more source

Chuck for delicate drills [PDF]

open access: yes, 1972
Development of oil film technique to couple power between drive spindle and drill chuck for delicate drilling operations is discussed. Oil film permits application of sufficient pressure, but stops rotating when drill jams.
Copeland, C. S.
core   +1 more source

The effect of foot orthoses on midfoot pain and the volume of bone marrow lesions in the midfoot: a randomized mechanism of action study

open access: yesArthritis Care &Research, Accepted Article.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain and MRI‐confirmed midfoot BMLs.
Jill Halstead   +4 more
wiley   +1 more source

Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics

open access: yesAdvanced Engineering Materials, EarlyView.
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani   +2 more
wiley   +1 more source

PENGARUH PROJECT BASED LEARNING DENGAN METODE DRILL DAN PROJECT BASED LEARNING DENGAN METODE FEEDBACK TERHADAP HASIL BELAJAR PEMROGRAMAN WEB

open access: yesTeknologi dan Kejuruan, 2018
Tujuan penelitian adalah mengungkap perbedaan rerata hasil belajar pem­rog­raman web (ranah pengetahuan dan keterampilan) karena pengaruh penerapan PjBL dan Metode Drill dibandingkan dengan PjBL dan metode Feedback.
Syaichul Fitrian Akbar   +2 more
doaj   +1 more source

Drill Based Model of Forehand Drive Practice in Table Tennis for Beginner Athlete

open access: yesActive: journal of physical education, sport, health and recreation, 2020
The purpose of study was to develop drill based model of forehand drive practice in table tennis for beginner athlete. The forehand drive had important role in table tennis playing.
Bessy Sitorus Pane   +2 more
doaj   +1 more source

Technique for anchoring fasteners to honeycomb panels [PDF]

open access: yes, 1969
Two-piece fastener bushing provides mounting surface for components on a three-inch thick honeycomb structure. Specially constructed starter drill and sheet metal drill permit drilling without misalignment.
Brown, W. J.   +2 more
core   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

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