Results 121 to 130 of about 809,394 (251)
Advanced Science, EarlyView.Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu +16 more
wiley +1 more source
Adolescent Drinking and High School Dropout [PDF]
This paper estimates the effect of binge and frequent drinking by adolescents on subsequent high school dropout using data from the National Longitudinal Survey of Youth 1979 Young Adults.
Pinka Chatterji, Jeff DeSimone
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Advanced Science, EarlyView.A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang +9 more
wiley +1 more source
Post-wildfire monitoring guidance for drinking water systems
, 2020 Title from PDF caption (viewed on November 20, 2020).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.
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IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis
Advanced Science, EarlyView.The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui +12 more
wiley +1 more source
Advanced Science, EarlyView.A transpiration‐inspired Janus nanofiber membrane creates a persistent dry‐wet interface that couples localized solar heating with hydration‐induced ion regulation. The asymmetric architecture sustains directional water and ion transport, suppresses salt accumulation, and enables simultaneous seawater evaporation and stable electricity generation ...
Qin Su +10 more
wiley +1 more source
Advanced Science, EarlyView.A yolk–shell PTFE‐based composite (YSP) enables tunable, robust hydrophobic–water interfaces for efficient, on‐demand sonocatalytic H2O2 generation and pollutant degradation. ABSTRACT The use of polytetrafluoroethylene (PTFE) particles to promote sonochemical H2O2 production has attracted growing interest, as cavitation bubbles formed at or near their ...
Rong Wang +6 more
wiley +1 more source
Does Drinking Impair College Performance? Evidence from a Regression Discontinuity Approach [PDF]
This paper examines the effect of alcohol consumption on student achievement. To do so, we exploit the discontinuity in drinking at age 21 at a college in which the minimum legal drinking age is strictly enforced. We find that drinking causes significant
Scott E. Carrell +2 more
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Advanced Science, EarlyView.ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou +9 more
wiley +1 more source
Using Mobile Technology to Study Episodes of Alcohol Self-Administration in Daily Life: A Narrative Review. [PDF]
Curr Addict RepFridberg DJ +4 more
europepmc +1 more source