Results 121 to 130 of about 1,690,287 (311)

A gut-to-brain signal of fluid osmolarity controls thirst satiation. [PDF]

, 2019
Satiation is the process by which eating and drinking reduce appetite. For thirst, oropharyngeal cues have a critical role in driving satiation by reporting to the brain the volume of fluid that has been ingested1-12.
Ahn, Jamie S, Bai, Ling, Beutler, Lisa R, Chen, Yiming, Corpuz, Timothy V, Huey, Erica L, Knight, Zachary A, Kosar, Seher, Madisen, Linda, Tan, Chan Lek, Zeng, Hongkui, Zimmerman, Christopher A   +11 more
core   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Social facilitation between commercial broilers and Nigerian indigenous chicks and its effect on their welfare

Agricultura Tropica et Subtropica, 2018
This study was undertaken to investigate how social facilitation between two chicken breeds could affect their welfare. Sixty chicks each of a commercial broiler (CB) and Nigerian indigenous chicken (NIC) breed were used for this study.
Iyasere Oluwaseun Serah, Oyeniran Victor Juwon, Oyawale Oluwatobiloba, Adeniyi Deborah, Uyanga Victoria Anthonia   +4 more
doaj   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Association Between Low-Carbohydrate Diet Scores and Incidence of Hypertension Among the Middle-Aged Japanese Population: The Toon Health Study

Dietetics
This study investigates the association between Low-Carbohydrate Diet (LCD) score and the incidence of hypertension in the Japanese population. This cohort study was conducted in an ongoing longitudinal study, the Toon Health Study.
Aziz Shoaib, Saori Miyazaki, Koutatsu Maruyama, Kiyohide Tomooka, Takeshi Tanigawa, Ryoichi Kawamura, Yasunori Takata, Haruhiko Osawa, Isao Saito   +8 more
doaj   +1 more source

Flaunting it on Facebook: Young adults, drinking cultures and the cult of celebrity [PDF]

, 2014
Copyright © Antonia Lyons; Tim McCreanor; Fiona Hutton; Ian Goodwin; Helen Moewaka Barnes; Christine Griffin; Kerryellen Vroman; Acushla Dee O’Carroll; Patricia Niland; Lina Samu Print publication available from: http://www.drinkingcultures.info/Young
Barnes, Helen Moewaka, Goodwin, Ian, Griffin, Christine, Hutton, Fiona, Kerryellen, Vroman, Lyons, Antonia, McCreanor, Tim, Niland, Patricia, O’Carroll, Acushla Dee, Samu, Lina   +9 more
core  

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

Advanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu, Xueting Ren, Zhen Zhai, Lu Wang, Liang Liang, Zengqi Tan, Jiazhen Zhao, Yuxuan Han, Yuhan Li, Feng Guan, Xiang Li   +10 more
wiley   +1 more source

Automated Identification of Unhealthy Drinking Using Routinely Collected Data: A Machine Learning Approach [PDF]

, 2019
Background: Unhealthy drinking is prevalent in the United States and can lead to serious health and social consequences, yet it is under-diagnosed and under-treated. Identifying unhealthy drinkers can be time-consuming for primary care providers.
Bonnell, Levi N., Littenberg, Benjamin, Rose, Gail L., Wshah, Safwan R.   +3 more
core   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

The Effects of Mindfulness on Brain Network Dynamics Following an Acute Stressor in a Population of Drinking Adults

Brain Sciences
Background: Previous research has found that mindfulness-based techniques are beneficial for reducing stress in heavy-drinking individuals. However, the underlying neurobiology of these stress-reducing effects are unclear.
Shannon M. O’Donnell, W. Jack Rejeski, Mohammadreza Khodaei, Robert G. Lyday, Jonathan H. Burdette, Paul J. Laurienti, Heather M. Shappell   +6 more
doaj   +1 more source