Results 201 to 210 of about 879,918 (311)

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non‐small Cell Lung Cancer

Advanced Science, EarlyView.
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin, Yongbiao Huang, Bin Li, Yuan Wang, Yan Li, Zhirui Chen, Zhe Tang, Chaofan Liu, Lei Zhang, Xianglin Yuan, Jianbo Tian, Bo Liu   +11 more
wiley   +1 more source

Hemodynamics and Drinking in the Giraffe. [PDF]

Acta Physiol (Oxf)
Aalkjær C, Damkjær M, Baandrup UT, Bertelsen MF, Brøgger T, Brøndum E, Danielsen CC, Funder JA, Grøndahl C, Hasenkam JM, Henriksen PG, Secher NH, Skovgaard N, Smerup MH, Telinius N, Østergaard KH, Bie P, Wang T.   +17 more
europepmc   +1 more source

A Touch Enabled Hemodynamic and Metabolic Monitor

Advanced Science, EarlyView.
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi, Tamoghna Saha, Ponnusamy Nandhakumar, Muhammad Inam Khan, Hannah Fishman, Sara Earney, Chochanon Moonla, Yuchen Xu, Henry Thai, Sofia Morales‐Fermin, Gyeongho Kim, Rhea Park, Beya Acot, Oscar Wu, Cannon Wurster, An‐Yi Chang, Christopher Cheung, Julia Silberman, Shichao Ding, Joseph Wang   +19 more
wiley   +1 more source

Effect of the MyDéfi Smartphone Application on Binge Drinking Among University Students: Protocol of a Double-Blind Multicenter Prospective National Randomized Controlled Trial Using Phosphatidylethanol as a Biomarker-The SMARTBINGE Trial. [PDF]

Int J Methods Psychiatr Res
André C, Sauton P, Dreinaza M, Diouf M, Bodeau S, Martinetti M, Trouillet R, de Groote C, Nandrino JL, Alexandre A, Benzerouk F, Gierski F, Perney P, Grellet L, André J, Naassila M.   +15 more
europepmc   +1 more source

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

Advanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen, Jianqiang Yang, David O. Popoola, Fan Yang, Yajie Liu, Dongsheng Wang, Zhaohui S. Qin, Zhengjia Chen, Nabil F. Saba, Zhuo G. Chen, Yamin Li, Yong Teng   +11 more
wiley   +1 more source

Microbial Water Quality at the Point of Use: The Role of Socio-Economic Factors and Water Handling Practices in Kitwe District, Zambia. [PDF]

Environ Health Insights
Ng'andwe S, Ogendi GM, Muoria E, Ngoma J.   +3 more
europepmc   +1 more source

Two‐Step Tandem Catalysis for High‐Efficiency Ammonia Synthesis Via Nitrate Reduction on Anion‐Intercalated CoNi LDH and Cu/Cu2O

Advanced Science, EarlyView.
By integrating Cu/Cu2O and CoNi LDH, tandem kinetic descriptors, including a volcano curve, are employed to predict rate constants, facilitating ideal kinetic matching for efficient ammonia synthesis. The highest ammonia yield (1.12 mmol cm−2 h−1) and Faraday efficiency (99.78%) are achieved by rate matching between Cu/Cu2O and MoO4‐CoNi LDH.
Changzheng Lin, Weijia Li, Hao Chen, Jiangtao Feng, Mengyuan Zhu, Jinwen Shi, Mingtao Li, Bo Hou, Zhenyu Wang, Xin Chen, Jia Liu, Wei Yan   +11 more
wiley   +1 more source

The effects of alcohol use severity and polygenic risk on gray matter volumes in young adults. [PDF]

Front Psychiatry
Chen Y, Li HT, Luo X, Li G, Ide JS, Li CR.   +5 more
europepmc   +1 more source

Highly Stretchable, Self‐Healable, and Conductive Gelatin Methacryloyl Hydrogel for Long‐Lasting Wearable Tactile Sensors

Advanced Science, EarlyView.
Gelatin methacryloyl hydrogel, which possesses high stretchability, tensile strength, toughness, and autonomous self‐healing capability at room temperature, is developed through the introduction of interpenetrating networks, hierarchical hydrogen bonds (weak and strong H‐bonds), and borate ester bonds.
Zhikang Li, Bin Wang, Jijian Lu, Yumeng Xue, Jiaxiang Wang, Boqing Jia, Gengyu Han, Yihe Zhao, Muhammad Afzal Khan Qureshi, Lan Yu, Kang Zhao, Min Li, Ping Yang, Dejiang Lu, Libo Zhao   +14 more
wiley   +1 more source

Hold My Beer: The Linkage between Municipal Water and Brewing Location on PFAS in Popular Beverages. [PDF]

Environ Sci Technol
Hoponick Redmon J, DeLuca NM, Thorp E, Liyanapatirana C, Allen L, Kondash AJ.   +5 more
europepmc   +1 more source