Results 191 to 200 of about 6,448,369 (384)

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu   +8 more
wiley   +1 more source

Drinking to Cope Mediates the Association between Dyadic Conflict and Drinking Behavior: A Study of Romantic Couples during the COVID-19 Pandemic. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Hagen AEF   +9 more
europepmc   +1 more source

An Economic Analysis of Consumer Expenditures for Safe Drinking Water: Addressing Nitrogen Risk with an Averting Cost Approach [PDF]

open access: yes
This article presents a procedure for estimating averting expenditures through the analyses of two data sources: (1) packaged water sales from 18 national supermarket chain stores in the Columbus, Ohio Metropolitan Area (COMA); and (2) treatment ...
Hitzhusen, Frederick J.   +2 more
core   +1 more source

DOES ANGIOTENSIN II RECEPTOR ANTAGONIST LOSARTAN SUPPRESS DRINKING BEHAVIOR IN HEMODIALYSIS PATIENTS? [PDF]

open access: bronze, 2001
Noriaki Shimada   +5 more
openalex   +1 more source

A Peripheral Mechanism of Depression: Disturbed Intestinal Epithelial Per2 Gene Expression Causes Depressive Behaviors in Mice with Circadian Rhythm Disruption via Gut Barrier Damage and Microbiota Dysbiosis

open access: yesAdvanced Science, EarlyView.
Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang   +16 more
wiley   +1 more source

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