Results 181 to 190 of about 7,196,972 (380)

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen   +8 more
wiley   +1 more source

Pelaksanaan Hygiene Sanitasi Depot dan Pemeriksaan Kandungan Bakteri Escherichia Coli pada Air Minum Isi Ulang di Kecamatan Tanjungpinang Barat Tahun 2012 [PDF]

open access: yes, 2012
Sanitize Hygiene Implementation and Examination of Escherichia Coli Content on Refill Drinking Water Depot on Tanjung Pinang Barat Sub-District in 2012. Water represents one the requirement very important human being.
Simbolon, V. A. (Veronica)
core  

Corrosion Tendency of S235 Steel in 3.5% NaCl Solution and Drinking Water During Six Months of Exposure [PDF]

open access: gold
Daniela Laura Buruiană   +5 more
openalex   +1 more source

Depletion of tilmicosin residue in Gushi chickens following oral administration via drinking water [PDF]

open access: bronze, 2023
Mei Zhang   +7 more
openalex   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

open access: yesAdvanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian   +11 more
wiley   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

open access: yesAdvanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo   +16 more
wiley   +1 more source

Capacity Building for Lavumisa Irrigation Development Project: process documentation [PDF]

open access: yes
Water resource management / Multiple use / Project planning / Project management / Stakeholders / Agricultural cooperatives / Participatory management / Sugarcane / Irrigated farming / Water supply / Drinking water / Sanitation / Swaziland / Maplotini ...
Mhlanga, N., van Koppen, Barbara
core  

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