Results 151 to 160 of about 54,030 (263)

Enhancing Lentiviral Purification: Combining CIM QA Monolithic Columns With Design of Experiments Approach

open access: yesELECTROPHORESIS, EarlyView.
Lentiviral vector purification using QA CIM monolith anion‐exchange chromatography was optimized via 96‐well and DOE, increasing recovery from 20% to 90%. The process achieved 3.3‐log host cell protein reduction, decreased particle impurities, and showed high binding capacity, supporting large‐scale manufacturing.
Luka Bevc   +7 more
wiley   +1 more source

Laser neoureterocystostomy to treat ectopic ureters

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Ureteral ectopia is an uncommon but clinically important congenital abnormality in horses. If left untreated, it can lead to persistent dermatitis, urinary tract infections, and failure to thrive. Surgical correction is necessary, but traditional approaches have produced mixed results with high morbidity.
Caitlin Smith, Eric J. Parente
wiley   +1 more source

Soluble Nanomedicine Against Soluble Neurosensitizers to Effectively Relieve Osteoarthritis Pain and Joint Damage

open access: yesExploration, EarlyView.
Osteoarthritis pain arises not only from joint damage but also from inflammation, abnormal bone changes, and excessive nerve activation inside the joint. In this study, we developed an injectable nanomedicine, LAC, that responds to the acidic environment of osteoarthritic joints to locally release two approved drugs, reducing inflammation, limiting ...
Junyan Liu   +12 more
wiley   +1 more source

Vehicle Fires: Significant Fire Hazard in Transportation Infrastructure

open access: yesFire and Materials, EarlyView.
ABSTRACT Vehicle flammability poses a critical threat to transportation infrastructure, with recent fires in depots, tunnels, and car parks highlighting systemic vulnerabilities. These incidents often result in the total loss of vehicles and buildings, revealing the inadequacy of current fire safety standards for vehicle materials.
Anja Hofmann‐Böllinghaus   +2 more
wiley   +1 more source

Experimental Characterization of the Effects of Mineral‐Based Fire‐Retardant Admixtures on the Combustion Properties of Polyethylene Blends

open access: yesFire and Materials, EarlyView.
ABSTRACT The growing demand for flame retardant (FR) polymeric materials has highlighted the need to improve the combustion behaviour of highly flammable polymers such as polyethylene (PE). This study investigates the use of eco‐sustainable mineral FRs as a strategy to reduce heat release and smoke production during combustion, while improving the ...
Linda Vitaloni   +3 more
wiley   +1 more source

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