Results 231 to 240 of about 4,250,637 (303)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Gravity-driven Microfluidic Platform for High-throughput Culture and Inflammatory Stimulation of Human Articular Chondrocytes. [PDF]

Curr Protoc
Silva AMD, Lamghari M, Nguyen HT, Kettunen J, Mosser S, Singh P, Mobasheri A, Lorite GS, Rodrigues PC.   +8 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Characteristics of solid versus hematologic malignancies in people living with human immunodeficiency virus. [PDF]

BMC Infect Dis
Schwartz AM, Daoud N, Jameson WP, Vanchiere JA, Malek AE.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Maintenance dynamics in digital health public goods: a quasi-experimental study of issue resolution during the 2025 USAID funding disruption. [PDF]

Oxf Open Digit Health
Sheng J, Finnegan A.
europepmc   +1 more source

Correction to "REGBOT: Artificial Intelligence-Driven Compliance Automation for Global Pharmacogenomics Data Sharing (Abstract PS02.38)". [PDF]

Clin Pharmacol Ther
europepmc   +1 more source