Results 31 to 40 of about 4,250,637 (303)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Mixed-potential-driven catalysis [PDF]

, 2023
Mixed-potential-driven catalysis is expected to be a new heterogeneous catalytic mechanism that produces products different from those produced by thermal catalytic reactions without the application of external energy. Electrochemically, the mechanism is
Kotaro, Takeyasu, Nuning, Namari, Mo, Yan, Junji, Nakamura   +3 more
core   +2 more sources

Transition of El Niño to La Niña can be driven by regional perturbations a year ahead

Environmental Research Letters
Interannual forecasts provide skilful predictions of El Niño-Southern oscillation (ENSO) up to a year in advance, however our understanding of what drives the ensemble skill and diversity of outcomes across members is limited. Using a fully coupled ocean–
Chris Kent, Adam A Scaife, William J M Seviour, Nick Dunstone, Doug Smith, Sarah Ineson   +5 more
doaj   +1 more source

Study on the Relationship between the Structure and Pyrolysis Characteristics of Lignin Isolated from Eucalyptus, Pine, and Rice Straw through the Use of Deep Eutectic Solvent

Molecules, 2023
Understanding the pyrolysis product distributions of deep eutectic solvent (DES)-isolated lignins (DESLs) from different types of biomass is of great significance for lignin valorization.
Tengfei Li, Xin Jin, Xinyao Shen, Hangdan Liu, Ruiping Tong, Xuzhen Qiu, Junfei Xu   +6 more
doaj   +1 more source

The Eddy-Driven Thermocline [PDF]

Journal of Physical Oceanography, 2004
Abstract The role of baroclinic eddies in transferring thermal gradients laterally, and thus determining the stratification of the ocean, is examined. The hypothesis is that the density differences imposed at the surface by differential heating are a source of available potential energy that can be partially released by mesocale eddies ...
Cessi, P., M.Fantini
openaire   +3 more sources

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Effect of Bonding Temperature on Microstructure and Mechanical Properties during TLP Bonding of GH4169 Superalloy

Applied Sciences, 2019
The effect of bonding temperature on the microstructure and mechanical properties of transient liquid phase (TLP) joints of GH4169 superalloy was investigated.
Qing He, Dongdong Zhu, Duo Dong, Mengjia Xu, Anpeng Wang, Qiancheng Sun   +5 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source