Results 41 to 50 of about 28,418 (263)

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Driver Fatigue Detection System Using Electroencephalography Signals Based on Combined Entropy Features

Applied Sciences, 2017
Driver fatigue has become one of the major causes of traffic accidents, and is a complicated physiological process. However, there is no effective method to detect driving fatigue.
Zhendong Mu, Jianfeng Hu, Jianliang Min
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Fatigue Driver Alert System

International Journal of Scientific Research in Computer Science, Engineering and Information Technology
The rise in accidents caused by drivers who are too sleepy to drive has made advanced driver alert systems necessary. This research proposes a novel method for identifying drowsy drivers through the integration of GPS technology and physiological data, offering an inventive solution to this pressing problem.
null Dr. Mallikarjun M Kodabagi, null Afrah Ayub, null Mahima BK, null Shruthi Siva, null Apurva Korni   +4 more
openaire   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

How to Reduce Work-Related Road Deaths? Driver Fatigue Monitoring – Case Study

Promet (Zagreb)
Work-related road deaths are the leading cause of occupational death. These traffic accidents contribute to at least one quarter all work-related deaths. Key risk factors associated with driving for work are driver fatigue and speeding. Driver fatigue is
Jelica DAVIDOVIĆ, Dalibor PEŠIĆ, Boris ANTIĆ   +2 more
doaj   +1 more source

Effect of Split Condition and Driving Duration on Fatigue Based on Changes in Brain Wave Signals when Driving a Train Simulator [PDF]

SHS Web of Conferences
One of the causes of train accidents is driver fatigue. Train driver fatigue can be caused by sleep factors, known as split sleep. This study aims to assess the impact of split sleep on train driver fatigue.
Auliani Sevty, Teresa Maria, Cahyaningsih Aulia Rahma, Emanuele Clementine, Soetisna Herman Rahadian, Iridiastadi Hardianto   +5 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

IDSRN: Interpretable Dynamic System Recurrent Network for Driver Fatigue Assessment

Applied Sciences
Driver fatigue is a critical factor contributing to traffic accidents. Therefore, real-time and accurate recognition of driver fatigue states holds significant importance.
Bing Gao, Ying Yan, Chenmeng Huangfu, Jun Cai, Hao Wang   +4 more
doaj   +1 more source