Results 201 to 210 of about 349,476 (265)

Distinct cellular effects of myotonic dystrophy type 2 repeat-associated non-AUG tetrapeptides. [PDF]

open access: yesDis Model Mech
Marzullo M   +9 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A Driver Screening Method Based on Perception Ability Test of Dangerous Omen. [PDF]

open access: yesSensors (Basel)
Chen L   +11 more
europepmc   +1 more source

Driver Drowsiness Detection using Machine Learning and Deep Learning Techniques: A Systematic Review. [PDF]

open access: yesArch Acad Emerg Med
Ghaffari Fam S   +5 more
europepmc   +1 more source

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