Results 71 to 80 of about 109,274 (257)
INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENTAbstract The Driver Monitoring System (DMS) is an innovative solution aimed at reducing road accidents caused by driver fatigue, distraction, and other unsafe behaviors. Leveraging advanced technologies like Convolutional Neural Networks (CNNs) and YOLO object detection models, the system monitors critical parameters such as eye movements, blinking ...
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
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Design and Testing of a Wearable System for Monitoring Car Drivers
Applied SciencesThe increasing concern over driver safety has led to the development of various monitoring systems aimed at assessing the physiological state of drivers.
Julien Moinard +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Applied SciencesThis paper investigates the application of fuzzy logic to enhance situational awareness in Advanced Driver Assistance Systems (ADAS). Situational awareness is critical for drivers to respond appropriately to dynamic driving scenarios.
Goran Ferenc +3 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Driver Vigilance Monitoring System
International Journal for Research in Applied Science and Engineering TechnologyDriver doziness is a significant contributor to road accidents encyclopedically, challenging robust and real- time discovery systems. This paper presents a comprehensive motorist Alert Monitoring System using deep literacy and computer vision ways to descry motorist fatigue by assaying eye countries.
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Real Time Driver's Respiration Monitoring
Journal of Sensor Science and Technology, 2014 Abstract Real time driver’s respiration monitoring method for detecting driver’s drowsiness is investigated. The sensor to obtain driver’s res-piration signal was a piezoelectric pressure sensor attached at the abdominal region of the seat belt. The resistance of the pressure sensorwas changed according to the pressure applied to the seat belt due to ...
Jaehee Park, Jaewoo Kim, Jae-Cheon Lee
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source