Results 121 to 130 of about 4,756,152 (342)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Driving cycle development for Kuala Terengganu city using k-means method

International Journal of Electrical and Computer Engineering (IJECE), 2019
Driving cycle plays a vital role in the production and evaluating the performance of the vehicle. Driving cycle is a representative speed-time profile of driving behavior of specific region or city.
I. Anida, A. R. Salisa
semanticscholar   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

KUALA TERENGGANU DRIVING CYCLE DEVELOPMENT USING TARGET PARAMETER APPROACH

The driving cycle is critical in producing and evaluating the vehicle s performance A driving cycle is a set of speed time data used as a key input in car emission models In this article a driving cycle for Kuala Terengganu Malaysia is proposed and ...
Jabar, SN, WanYussof, WNJH, Anida, IN, Rahman, SA, Walker, PD   +4 more
core   +1 more source

Stochastic Driving Cycle Synthesis for Analyzing the Energy Consumption of a Battery Electric Bus

IEEE Access, 2018
Previous driving cycle generation studies have focused on constructing a single cycle from a large data set. This paper takes the opposite approach by presenting a novel driving cycle synthetization method that can generate a large number of varying ...
Klaus Kivekäs, Jari Vepsäläinen, K. Tammi   +2 more
semanticscholar   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A driving cycle for electrically-driven vehicles in Rome

, 2003
In the research results presented here, an average driving cycle is synthesized for an electrically driven car moving in the city of Rome. The technique of Lyons et al.
A Alessandrini, F Orecchini, ALESSANDRINI, Adriano, ORECCHINI, FABIO   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

City Bus Powertrain Comparison: Driving Cycle Variation and Passenger Load Sensitivity Analysis

Energies, 2018
Alternative powertrains are rapidly increasing in popularity in city buses. Hence, it is vitally important to understand the factors affecting the performance of the powertrains in order to operate them on appropriate routes and as efficiently as ...
Klaus Kivekäs, Antti Lajunen, Jari Vepsäläinen, K. Tammi   +3 more
semanticscholar   +1 more source

Flexibly Parameterizable Vehicle Dynamics Models

Designs
The following article presents the longitudinal modeling and simulation of a generic electric vehicle. The purpose of the research is to describe the applied modeling procedures and their MATLAB solutions.
Dániel Nemes, Sándor Hajdu
doaj   +1 more source