Results 31 to 40 of about 114,008 (265)

A Hand-Held Non-Robotic Surgical Device to Compensate for Wire Length in Unpredicted Paths

open access: yesIEEE Access, 2021
This paper describes a surgical device that uses a compensation mechanism without motors and electronics to reduce the backlash in the end-effector. The device improves the precision and accuracy of surgical operations that involve unpredictable curved ...
Jeongryul Kim   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Assessment of the Potential of Wrist-Worn Wearable Sensors for Driver Drowsiness Detection

open access: yesSensors, 2020
Drowsy driving imposes a high safety risk. Current systems often use driving behavior parameters for driver drowsiness detection. The continuous driving automation reduces the availability of these parameters, therefore reducing the scope of such methods.
Thomas Kundinger   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Investigation of the driving voltage on the high performance flexible ATF-ECDs based on PET/ITO/NiOX/LiTaO3/WO3/ITO

open access: yesHeliyon
High performance flexible all-thin-film electrochromic devices (ATF-ECDs) have been fabricated and systematically investigated by operating with different driving voltages during the electrochromic processes.
Jinhong Ye   +6 more
doaj   +1 more source

Development of assistive devices to support posture for spinal cord injury persons when driving a vehicle

open access: yesStudies in Science and Technology, 2020
For people with disabilities or walking difficulties in the limbs or trunk that interfere with driving a vehicle, the Japanese Road Traffic Law requires the installation of auxiliary equipment according to the degree of the disability.
Hiroshi Ikeda   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Road traffic injuries and fatalities among drivers distracted by mobile devices

open access: yesJournal of Emergencies, Trauma and Shock, 2018
Context: With increasing ownership of mobile devices (i.e., cell phones and smartphones), it is important to better understand the role of these devices in motor vehicle collision (MVC)-related trauma.
Natasa Zatezalo   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Research the load capacity of microcircuits

open access: yesФизика волновых процессов и радиотехнические системы, 2020
The device for the definition of the integrated circuits load-driving capability is offered. Device for determining the output capability of microcircuits refers to the field of microminiaturization and the technology of radio electronic equipment and ...
Katerina S. Yarantseva   +3 more
doaj   +1 more source

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