Results 121 to 130 of about 17,380,154 (353)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Characteristics and Driving Factors of Soil Salinisation in the Irrigated Area on the Southern Bank of the Yellow River in Inner Mongolia: A Assessment of the Donghaixin Irrigation District

Agriculture
Soil salinisation is a critical problem in northern China’s arid and semi-arid irrigated regions, posing a substantial impediment to the sustainable advancement of agriculture in these areas.
Ziyuan Qin, Tangzhe Nie, Ying Wang, Hexiang Zheng, Changfu Tong, Jun Wang, Rongyang Wang, Hongfei Hou   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Summertime compound heat wave and drought events in China: interregional and subseasonal characteristics, and the associated driving factors

Environmental Research Letters
This study investigates the characteristics of compound heat wave and drought events (CHDEs) across various subregions of China from 1961 to 2022 by utilizing a monthly probability-based index.
Jiani Zeng, Huixin Li, Bo Sun, Huopo Chen, Huijun Wang, Botao Zhou, Mingkeng Duan   +6 more
doaj   +1 more source

Transformations in Urban Human Settlements Within China’s Sustainable Development Innovation Demonstration Zones: A Case Study of Chenzhou City, Hunan Province, During Rapid Urbanization

Land
The quality of urban human settlements (UHSs) directly affects the city’s livability and the well-being of its residents. Scientific monitoring and assessment of UHSs, their progress toward sustainable development, and impacts they experience from rapid ...
Bingxin Xu, Penglong Wang, Yichun Wang, Qinhua Wang, Bao Wang, Xueyan Zhao, Junxia Miao, Feng Gao   +7 more
doaj   +1 more source

Landscape ecological risk assessment and its driving factors of multi-mountainous city

Ecological Indicators, 2023
Xun Lin, Zhitai Wang
semanticscholar   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Analysis of the Driving Mechanism of Grassland Degradation in Inner Mongolia Grassland from 2015 to 2020 Using Interpretable Machine Learning Methods

Land
In traditional studies on grassland degradation drivers, researchers often lacked the flexibility to selectively consider driving factors and quantitatively depict their contributions. Interpretable machine learning offers a solution to these challenges.
Zuopei Zhang, Yunfeng Hu, Batunacun
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Spatio-temporal variations of vegetation cover and its influencing factors in highland lake basin

Frontiers in Environmental Science
Exploring dynamic vegetation changes and identifying the factors driving these changes are important for evaluating global ecosystem processes. Based on the pixel binary model, coefficient of variation, Theil-Sen median trend analysis, geographic ...
Zhoujiang Liu, Wenxian Hu, Liming Ma, Xiaoxia Huang   +3 more
doaj   +1 more source