Results 51 to 60 of about 2,800,903 (302)

The influences of driving forces on behaviors of Na+ and H2O in cyclic octa-peptide nanotube: investigated by steered molecular dynamics

open access: yesMaterials Research Express, 2020
The behaviors of Na ^+ and H _2 O in cyclic peptide nanotube (CPN) under different conditions are important for their applications. In this study, a series of driving forces has been applied to Na ^+ and H _2 O constrained in the self-assembled nanotube ...
Tianjiao Shan   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Analysis of the Vertical Driving Performance of Multiple Connected Pipe-Climbing Microrobots with Magnetic Wheels

open access: yesMicromachines, 2019
In this study, we analyzed the vertical driving performance of multiple connected magnetic wheel-driven microrobots when moving up and down a small cylinder that simulated a pipe. The dynamics of pipe climbing by the magnetic wheel-driven microrobot were
Munehisa Takeda, Isao Shimoyama
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

DRIVING FORCE: SELF-DEFENCE AND DANGEROUS DRIVING [PDF]

open access: yes
In Riddell [2017] EWCA Crim 413, [2017] 1 W.L.R. 3593, the Court of Appeal held that self-defence could be a defence to an offence not inherently involving the use of force, namely, dangerous ...

core   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Cause analysis and prevention of tailings dam failures based on the AISM-MICMAC Model

open access: yes河南理工大学学报. 自然科学版
ObjectivesTo explore the relationships among the causes of tailings dam failures, examine the evolution paths of different factors, analyze the driving-dependence relationships, identify the factors with high driving force and high dependence, and ...
Ye Jiawen   +4 more
doaj   +1 more source

DRIVING FORCE: SELF-DEFENCE AND DANGEROUS DRIVING

open access: yes, 2018
InRiddell [2017] EWCA Crim 413, [2017] 1 W.L.R. 3593, the Court of Appeal held that self-defence could be a defence to an offence not inherently involving the use of force, namely, dangerous driving.
Elaine Freer
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Other title: Task force report and recommendations

open access: yes, 2019
"April 25, 2019."; "Created: 4/24/2019..."-Document properties screen.; In 2018, the Ohio Department of Transportation (ODOT) and the Ohio Department of Public Safety (ODPS) convened a Distracted Driving Task Force with more than 30 stakeholders from ...
Ohio Distracted Driving Task Force,
core  

Home - About - Disclaimer - Privacy