Continental rifts losing driving forces can still complete breakup. [PDF]
Silva KCC, Choi E.
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Driving forces for the subcellular localization of peripheral proteins.
Driving forces for the subcellular localization of peripheral ...
Robert Virgil. Stahelin (7969454)
core
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Metabolic dependencies and neural progenitor dysregulation: driving forces in paediatric high-grade glioma development. [PDF]
Lee YHG +4 more
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Study of Driving Forces for Atomic Migration in Dilute Alloys
We present a pseudopotential calculation of the driving forces for atomic migration in the 156 dilute alloys of the 23 host of the different groups of the periodic table in the presence
M. Vora, Aditya
core +1 more source
Identifying the coupling coordination relationship and driving forces between urbanization and the supply-demand of ecosystem service: a case study of the Gansu Province. [PDF]
Dang G, Hu J, Li G.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
The purpose of this policy synthesis is to document major shifts in output and provide hypotheses about the reasons behind the changes. The paper also documents troubling trends in the traditional agriculture sector, underscoring the need for improved ...
Loveridge, Scott +2 more
core +1 more source

