Results 81 to 90 of about 776,236 (287)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Vibrotactile pedals : provision of haptic feedback to support economical driving [PDF]

open access: yes, 2013
The use of haptic feedback is currently an underused modality in the driving environment, especially with respect to vehicle manufacturers. This exploratory study evaluates the effects of a vibrotactile (or haptic) accelerator pedal on car driving ...
Adell E.   +32 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

An FPGA-Based Neuro-Fuzzy Sensor for Personalized Driving Assistance

open access: yesSensors, 2019
Advanced driving-assistance systems (ADAS) are intended to automatize driver tasks, as well as improve driving and vehicle safety. This work proposes an intelligent neuro-fuzzy sensor for driving style (DS) recognition, suitable for ADAS enhancement. The
Óscar Mata-Carballeira   +3 more
doaj   +1 more source

Magnetocaloric materials: the search for new systems

open access: yes, 2012
The prospect of efficient solid state refrigeration at room temperature is driving research into magnetic cooling engine design and magnetic phase transition-based refrigerants.
Sandeman, Karl G.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A Computationally Efficient Model Predictive Control Energy Management Strategy for Hybrid Vehicles Considering Driving Style

open access: yesIEEE Access
In this study, a computationally efficient energy management strategy for model predictive control for hybrid vehicles considering the driving style is proposed.
Yalian Yang, Yuqi Chen, Changdong Liu
doaj   +1 more source

Are You Used To It Yet? Braking Performance and Adaptation in a Fixed-base Driving Simulator. [PDF]

open access: yes, 2003
During braking-to-stop manoeuvres in a fixed-base driving simulator, the paucity of visual and vestibular cues can lead to driver misperception and produce different patterns of braking response between real and simulated driving.
Jamson, A.H., Smith, P.
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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