Results 131 to 140 of about 935,592 (269)

The biarticularity of the gastrocnemii muscles provides relevant mechanisms for managing drop-like gait perturbations in humans. [PDF]

J Exp Biol
Theodorakis C, Bohm S, Mersmann F, Arampatzis A.   +3 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Drop metastasis in glioblastoma multiforme

Indian Journal of Medical and Paediatric Oncology, 2020
Mintu Mathew, T M Anoop, P Rona Joseph
doaj   +1 more source

Sugar-mediated physical constraints drive the evolution of pollination drops into nectar. [PDF]

Sci Rep
Giordano E, Betti G, Calabrese D, Casino CD, Ferrari M, Cirisano F, Gasperi T, Nepi M.   +7 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Experimental and computational models for intracardiac flow analysis with blood speckle imaging. [PDF]

PLoS One
Laughlin M, Jack JT, Stephens SE, Bolin E, Millett PC, Jensen MO.   +5 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Feasibility and Safety of High-Power Settings for Electrical Isolation of the Superior Vena Cava Using a Catheter Capable of Local Impedance and Contact Force Monitoring. [PDF]

J Arrhythm
Kawano D, Mori H, Matsumoto K, Tanaka N, Naganuma T, Sasaki W, Narita M, Matsumoto K, Ikeda Y, Matsumoto K, Kato R.   +10 more
europepmc   +1 more source