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Droplet-based microfluidics [PDF]

, 2019
In this thesis, the background of both microfluidics and droplet-based microfluidics are first introduced and presented. Next, the objectives and scopes are defined to give a clear understanding on the research topic. The literature of droplet formation in different configurations is then reviewed thoroughly through many different past works.
Werner Haselmayr, Andrea Zanella, Giacomo Morabito   +2 more
openaire   +3 more sources

Pico-washing: simultaneous liquid addition and removal for continuous-flow washing of microdroplets

Microsystems & Nanoengineering, 2022
Droplet microfluidics is based on a toolbox of several established unit operations, including droplet generation, incubation, mixing, pico-injection, and sorting. In the last two decades, the development of droplet microfluidic systems, which incorporate
Michael J. Siedlik, David Issadore
doaj   +1 more source

Droplet-based microfluidics in biomedical applications

Biofabrication, 2022
Abstract Droplet-based microfluidic systems have been employed to manipulate discrete fluid volumes with immiscible phases. Creating the fluid droplets at microscale has led to a paradigm shift in mixing, sorting, encapsulation, sensing, and designing high throughput devices for biomedical applications.
Leyla Amirifar, Mohsen Besanjideh, Rohollah Nasiri, Amir Shamloo, Fatemeh Nasrollahi, Natan Roberto de Barros, Elham Davoodi, Ahmet Erdem, Mahboobeh Mahmoodi, Vahid Hosseini, Hossein Montazerian, Jamileh Jahangiry, Mohammad Ali Darabi, Reihaneh Haghniaz, Mehmet R Dokmeci, Nasim Annabi, Samad Ahadian, Ali Khademhosseini   +17 more
openaire   +5 more sources

High-throughput screening of microbial strains in large-scale microfluidic droplets

Frontiers in Bioengineering and Biotechnology, 2023
The transformation of engineered microbial cells is a pivotal link in green biomanufacturing. Its distinctive research application involves genetic modification of microbial chassis to impart targeted traits and functions for effective synthesis of the ...
Zhidong Zhang, Zhidong Zhang, Zhidong Zhang, Qi Guo, Qi Guo, Yuetong Wang, He Huang, He Huang   +7 more
doaj   +1 more source

Droplet-Based Pyrosequencing Using Digital Microfluidics [PDF]

Analytical Chemistry, 2011
The feasibility of implementing pyrosequencing chemistry within droplets using electrowetting-based digital microfluidics is reported. An array of electrodes patterned on a printed-circuit board was used to control the formation, transportation, merging, mixing, and splitting of submicroliter-sized droplets contained within an oil-filled chamber.
Deborah J, Boles, Jonathan L, Benton, Germaine J, Siew, Miriam H, Levy, Prasanna K, Thwar, Melissa A, Sandahl, Jeremy L, Rouse, Lisa C, Perkins, Arjun P, Sudarsan, Roxana, Jalili, Vamsee K, Pamula, Vijay, Srinivasan, Richard B, Fair, Peter B, Griffin, Allen E, Eckhardt, Michael G, Pollack   +15 more
openaire   +2 more sources

Droplet acoustofluidics: From acoustic principles to micro manipulations [PDF]

Nanotechnology and Precision Engineering
Droplet-based microfluidics have drawn much attention in recent years and have been successfully applied in biochemical analysis, material synthesis, and biomedical engineering.
Xianwu Ke, Xiaotian Shen, Tiechuan Li, Xuexin Duan   +3 more
doaj   +1 more source

Deep learning with microfluidics for on-chip droplet generation, control, and analysis

Frontiers in Bioengineering and Biotechnology, 2023
Droplet microfluidics has gained widespread attention in recent years due to its advantages of high throughput, high integration, high sensitivity and low power consumption in droplet-based micro-reaction.
Hao Sun, Hao Sun, Wantao Xie, Wantao Xie, Jin Mo, Jin Mo, Yi Huang, Hui Dong, Hui Dong   +8 more
doaj   +1 more source

DNA sequence analysis with droplet-based microfluidics [PDF]

Lab on a Chip, 2013
Droplet-based microfluidic techniques can form and process micrometer scale droplets at thousands per second. Each droplet can house an individual biochemical reaction, allowing millions of reactions to be performed in minutes with small amounts of total reagent.
Abate, Adam R, Hung, Tony, Sperling, Ralph A, Mary, Pascaline, Rotem, Assaf, Agresti, Jeremy J, Weiner, Michael A, Weitz, David A   +7 more
openaire   +4 more sources

A self-triggered picoinjector in microfluidics

AIP Advances, 2016
Droplet-based microfluidics has recently emerged as a potential platform for studies of single-cell, directed evolution, and genetic sequencing. In droplet-based microfluidics, adding reagents into drops is one of the most important functions.
Yiming Yang, Songsheng Liu, Chunping Jia, Hongju Mao, Qinghui Jin, Jianlong Zhao, Hongbo Zhou   +6 more
doaj   +1 more source

Surfactants in droplet-based microfluidics [PDF]

Lab Chip, 2012
Surfactants are an essential part of the droplet-based microfluidic technology. They are involved in the stabilization of droplet interfaces, in the biocompatibility of the system and in the process of molecular exchange between droplets. The recent progress in the applications of droplet-based microfluidics has been made possible by the development of
openaire   +4 more sources