Results 51 to 60 of about 11,691 (151)

Performance of nanoliter-sized droplet-based microfluidic PCR [PDF]

Biomedical Microdevices, 2009
A microfluidic device was used to characterize PCR in aqueous-in-oil droplets for potential point-of-care applications. Droplets with a volume range of 5-250 nL can be formed on-chip reproducibly, and PCR in the droplets shows amplification efficiencies comparable to benchtop reactions with no evaporation loss.
Fang, Wang, Mark A, Burns
openaire   +2 more sources

Exploring whey and faba bean protein interactions at the oil-water interface: A combined drop tensiometry and microfluidicsstudy

Current Research in Food Science
The interfacial properties of model oil–water interfaces stabilized by faba bean protein isolate (FPI), whey protein isolate (WPI), and their mixtures were investigated. Two complementary techniques, microfluidics-based analysis and drop tensiometry were
Dionysios D. Neofytos, Katherine F. Grasberger, Anders Holste, Sandra B. Gregersen, Claus H. Christensen, Milena Corredig   +5 more
doaj   +1 more source

Droplet‐based microfluidics for microtoxicological studies

Engineering in Life Sciences, 2015
The specific sensitivity of different organisms, cells, and tissues against chemicals, the huge number of produced and applied substances, and the combinatorial explosion of effects by the combination of substances demand new concepts for the efficient determination of toxicological dose/response relations.
Jialan Cao, Johann Michael Köhler
openaire   +1 more source

Recent Progress in Droplet Structure Machining for Advanced Optics

Micromachines
The development of optical and photonic applications using soft-matter droplets holds great scientific and application importance. The machining of droplet structures is expected to drive breakthroughs in advancing frontier applications.
Jin-Kun Guo, W.D.N. Sandaruwan, Jinwei Li, Jinzhong Ling, Ying Yuan, Xin Liu, Qiang Li, Xiaorui Wang   +7 more
doaj   +1 more source

Interface evolution of microdroplets in flow-focusing channels with varying aspect ratios

Flow
This study combines experimental observations and numerical simulations to comprehensively analyse the interface evolution of confined droplets in microfluidic devices with flow-focusing junctions under different aspect ratios.
Luyao He, Bo Wang, Qingquan Liu, Xiaodong Chen   +3 more
doaj   +1 more source

Editorial for the Special Issue on Droplet-Based Microfluidics: Design, Fabrication, and Applications. [PDF]

Micromachines (Basel), 2023
Zhu P.
europepmc   +1 more source

dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments

Genome Biology, 2018
Recent single-cell RNA-seq protocols based on droplet microfluidics use massively multiplexed barcoding to enable simultaneous measurements of transcriptomes for thousands of individual cells. The increasing complexity of such data creates challenges for
Viktor Petukhov, Jimin Guo, Ninib Baryawno, Nicolas Severe, David T. Scadden, Maria G. Samsonova, Peter V. Kharchenko   +6 more
doaj   +1 more source

Deep learning enabled label-free microfluidic droplet classification for single cell functional assays

Frontiers in Bioengineering and Biotechnology
Droplet-based microfluidics techniques coupled to microscopy allow for the characterization of cells at the single-cell scale. However, such techniques generate substantial amounts of data and microscopy images that must be analyzed.
Thibault Vanhoucke, Thibault Vanhoucke, Angga Perima, Lorenzo Zolfanelli, Lorenzo Zolfanelli, Pierre Bruhns, Pierre Bruhns, Matteo Broketa, Matteo Broketa, Matteo Broketa   +9 more
doaj   +1 more source

Design of microfluidic chromatographs through reinforcement learning

Digital Chemical Engineering
Chromatography is one of the most valuable techniques chemists possess at their disposal, conducive to everything from developing vaccines, food, beverage, and drug testing to catching criminals.
Mohammad Shahab, Raghunathan Rengaswamy
doaj   +1 more source

Recent advances in droplet‐based microfluidics in liquid biopsy for cancer diagnosis

Droplet
Liquid biopsy, a noninvasive technique to obtain tumor information from body fluids, is an emerging technology for cancer diagnosis, prognosis, and monitoring, providing crucial support for the realization of precision medicine.
Jingyu Shi, Yu Zhang, Yadi Fan, Yi Liu, Mo Yang   +4 more
doaj   +1 more source