Results 101 to 110 of about 512,844 (338)

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

open access: yesAdvanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei   +12 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

open access: yesAdvanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu   +10 more
wiley   +1 more source

School dropouts or pushouts? Overcoming barriers for the right to education [PDF]

open access: yes, 2010
Persistently high dropout rates are one of the biggest challenges to fulfilling the right to education in India. This paper attempts to assess the magnitude of the problem of dropout.
Reddy, Anugula N., Sinha, Shantha
core  

Variational Dropout via Empirical Bayes [PDF]

open access: green, 2018
В. А. Харитонов   +2 more
openalex   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

open access: yesAdvanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng   +13 more
wiley   +1 more source

Improving the Automatic Detection of Dropout Risk in Middle and High School Students: A Comparative Study of Feature Selection Techniques

open access: yesMathematics
The dropout rate in underdeveloped and emerging countries is a pressing social issue, as highlighted by studies conducted by The Organization for Economic Co-operation and Development. This study compares five feature selection techniques to address this
Daniel Zapata-Medina   +2 more
doaj   +1 more source

Meeting the Challenge: Fiscal Implications of Dropout Prevention in Massachusetts [PDF]

open access: yes, 2011
In 2009, for the first time in a decade, Massachusetts' dropout rate fell below three percent. While this progress is promising, there remain nearly 8,300 students who did not earn their high school diplomas during the 2009-2010 school year.

core  

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

open access: yesAdvanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu   +5 more
wiley   +1 more source

Rethinking treatment failures. Research on a group of Italian psychotherapists

open access: yesFrontiers in Psychology
IntroductionPsychotherapeutic failures involve situational, relational, and personal factors. Dropout refers to a patient’s unilateral termination of treatment without the therapist’s knowledge or approval.
Osmano Oasi   +5 more
doaj   +1 more source

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