Results 41 to 50 of about 5,123 (248)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Pantograph lift force evaluation based on contact wire uplift using self-organizing maps

open access: yesNihon Kikai Gakkai ronbunshu
This paper proposes a non-contact method for detecting deviations in pantograph aerodynamic lift using contact wire uplift measured by general-purpose cameras installed along the railway line.
Yoshitaka YAMASHITA   +3 more
doaj   +1 more source

Application via mechanical dropper alleviates sufentanil-induced cough: a prospective, randomized, single-blinded trial

open access: yesTrials, 2019
Background It was reported that prolonging the injection time or diluting administration can reduce the incidence of opioid-induced cough. However, the incidence of sufentanil-induced cough (SIC) via a standardized infusion rate is unclear.
Minqiang Liu   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Effect of the farming intensification on health-promoting compounds in the meat of the Mediterranean mussel Mytilus galloprovincialis

open access: yesAquaculture Reports
This study investigated the effect of increasing levels of farming intensification on some health-promoting compounds present in the meat of the Mediterranean mussel Mytilus galloprovincialis in the Northern Coastal Area of Gargano, Italy, during the ...
Antonella della Malva   +3 more
doaj   +1 more source

Lord Kelvin's atmospheric electricity measurements [PDF]

open access: yesHistory of Geo- and Space Sciences, 2013
Lord Kelvin (William Thomson) made important contributions to the study of atmospheric electricity during a brief but productive period from 1859–1861. By 1859 Kelvin had recognised the need for "incessant recording" of atmospheric electrical parameters,
K. L. Aplin, R. G. Harrison
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Computational fluid dynamics approaches to drag and wake of a long-line mussel dropper under tidal current

open access: yesScience Progress, 2020
Hydrodynamic effects of mussel farms have attracted increased research attentions in recent years. The understanding of the hydrodynamic impacts is essential for predicting the sustainability of mussel farms.
Zhijing Xu   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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