Results 141 to 150 of about 1,736,644 (327)
The outcome of a drop impact event depends on many parameters. In this thesis, we focused on how three different substrate properties influence the splashing behavior of impacting drops. These properties can be used to control splashing in the extreme ultraviolet (EUV) source chamber of lithography machines produced by ASML.We measured and modeled how ...
openaire +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Interesting Cases of Wrist Drops and Foot Drops
Lead exposures occur through many routes to the human body in a wide range of occupations. Chronic lead exposure can lead to a myriad of symptoms and signs. The most common manifestations are neurological.
Sunil Kumar Mahavar +3 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
This article examines how individuals of diverse cultural backgrounds in Norway participate in anti-racist activism via social media. It investigates the nature of digital activism compared to traditional paradigms, highlighting the varied forms of ...
Cecilia Salinas
doaj +1 more source
The present study aimed to investigate and compare the laboratory results of energy dissipation and length of vertical Drops equipped with horizontal Screens with the results of standard stilling basins of type one, two, three and four simple vertical ...
R. Daneshfaraz +2 more
doaj
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A Neoclassical Analysis of the Asian Crisis: Business Cycle Accounting of a Small Open Economy [PDF]
This paper applies the business cycle accounting method a la Chari, Kehoe and McGrattan (2007) to a standard neoclassical small open economy model and assesses the recent crises in Hong Kong, Korea, Singapore and Thailand.
Keisuke Otsu
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source

