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Death of dopaminergic (DAergic) neurons in the substantia nigra pars compacta of the human brain is the characteristic pathological feature of Parkinson’s disease (PD).
Mohamad Ayajuddin +8 more
doaj +1 more source
Generation of Drosophila attP containing cell lines using CRISPR-Cas9
The generation of Drosophilain vivoDrosophilaDrosophilaDrosophila melanogasterin vivoDrosophilaD ...
Daniel Mariyappa +3 more
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Background Various bleaching agents are used in food industries among which some reacts to form alloxan. Therefore, the alloxan can indirectly enter a human body and thus form an important aspects for studying its effect on the development.
Yasir Hasan Siddique +6 more
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p120 catenin is required for the stress response in Drosophila [PDF]
p120ctn is a ubiquitously expressed core component of cadherin junctions and essential for vertebrate development. Surprisingly, Drosophila p120ctn (dp120ctn) is dispensable for adherens junctions and development, which has discouraged Drosophila ...
Bauer, Christin +2 more
core +8 more sources
Background: Seizure disorders are considered a serious health issue because of the vast number of people affected globally and the limited treatment options.
Sara Moghimi, B.P. Harini
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Drosophila melanogaster Chemosensory Pathways as Potential Targets to Curb the Insect Menace
From a unicellular bacterium to a more complex human, smell and taste form an integral part of the basic sensory system. In fruit flies Drosophila melanogaster, the behavioral responses to odorants and tastants are simple, though quite sensitive, and ...
Md Zeeshan Ali +3 more
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Millions of people in developing countries are affected by arsenic (As) toxicity and its prevalence. Arsenic’s detrimental effects on humans have been amplified by an unacceptable level of exposure to food and drinking water, the ongoing rise in ...
Anushree +3 more
doaj +1 more source
Macrophage-derived upd3 Cytokine causes impaired glucose homeostasis and reduced lifespan in drosophila fed a lipid-rich diet [PDF]
Long-term consumption of fatty foods is associated with obesity, macrophage activation and inflammation, metabolic imbalance, and a reduced lifespan. We took advantage of Drosophila genetics to investigate the role of macrophages and the pathway(s) that ...
Dionne, MS +5 more
core +1 more source
Roles of Drosophila Hox Genes in the Assembly of Neuromuscular Networks and Behavior
Hox genes have been known for specifying the anterior-posterior axis (AP) in bilaterian body plans. Studies in vertebrates have shown their importance in developing region-specific neural circuitry and diversifying motor neuron pools. In Drosophila, they
Rohit Joshi +4 more
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