Results 91 to 100 of about 559,429 (351)

Drosophila montium

, 2006
Published as part of Schiffer, Michele & Mcevey, Shane F., 2006, Drosophila bunnanda — a new species from northern Australia with notes on other Australian members of the montium subgroup (Diptera: Drosophilidae), pp.
Schiffer, Michele, Mcevey, Shane F.
openaire   +2 more sources

Microfilament‐Myosin II Regulates the Differentiation of Multinucleated Cysts into Oocytes and Influences Oocyte Developmental Potential in Mice

Advanced Science, EarlyView.
In this study, we provided new evidence identifying multinucleated cysts as precursors for oocyte differentiation. Within these cysts, organelles migrate and aggregate to form Balbiani body (B‐body) and establish early cellular polarity. Concurrently, excess nuclei are expelled, enabling cyst‐to‐oocyte differentiation. The microfilament‐myosin II plays
Rui Xu, Menghao Pan, Zhi Zheng, Yaju Tang, Yutong Yan, Sihai Lu, Sha Peng, Baohua Ma   +7 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Phylogeny of the Genus Drosophila

Genetics, 2018
Understanding phylogenetic relationships among taxa is key to designing and implementing comparative analyses. The genus Drosophila, which contains over 1600 species, is one of the most important model systems in the biological sciences.
P. O'Grady, R. DeSalle
semanticscholar   +1 more source

Ubiquitination‐Dependent LLGL2 Degradation Drives Colorectal Cancer Progression via THBS3 mRNA Stabilization

Advanced Science, EarlyView.
During the progression of CRC, MDM2, as an E3 ubiquitin ligase, promotes the degradation of the LLGL2 protein. Reduced expression of the LLGL2 protein leads to the loss of support for the CNOT1 protein, decreasing the degradation of THBS3 mRNA. The increased THBS3 further activates the PI3K‐Akt pathway, promoting the proliferation and metastasis of CRC.
Jiayan Huang, Tiantian Zhang, Huimin Li, Zidan Li, Shuangshuang Yin, Yiman Liu, Chunze Zhang, Yuling Qiu, Haiyang Yu   +8 more
wiley   +1 more source

Beneficial Role of Coffee and Caffeine in Neurodegenerative Diseases: A Minireview

AIMS Public Health, 2016
Coffee is among the most widespread and healthiest beverages in the world. Coffee typically contains more caffeine than most other beverages, and is widely and frequently consumed.
Yenisetti SC, Muralidhara
doaj   +1 more source

Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair in Drosophila

Genetics, 2014
We and others recently demonstrated that the readily programmable CRISPR/Cas9 system can be used to edit the Drosophila genome. However, most applications to date have relied on aberrant DNA repair to stochastically generate frameshifting indels and ...
S. Gratz, Fiona P. Ukken, C. D. Rubinstein, Gene H Thiede, Laura K Donohue, Alexander M. Cummings, Kate M. O’Connor-Giles   +6 more
semanticscholar   +1 more source

Progastrin Promotes Colorectal Cancer Stem Cell‐Like Properties via the Receptor PZR

Advanced Science, EarlyView.
The tumor microenvironment supports colorectal cancer (CRC) progression by maintaining cancer stem cells (CSCs) through progastrin (PG). This study identifies Protein Zero‐Related protein (PZR) as an essential receptor for PG activity, promoting CSC‐like signaling via SHP2/SRC/β‐catenin.
Julie Nguyen, Marie Lafitte, Maud Barbery, Kevin Espie, Maya Jeitany, Romain Larive, Jihane Vitre, Conception Paul, Yvan Boublik, Elise Fourgous, Valérie Simon, Audrey Sirvent, Madeline Neiveyans, Steeve Thirard, Lucile Bansard, Morgan Maillard, Nathalie Coutry, Jacques Colinge, Philippe Jay, Pierre Martineau, Michael Hahne, Julie Pannequin, Serge Roche   +22 more
wiley   +1 more source

Biogenic silver nanoparticles from Simarouba glauca DC leaf extract: Synthesis, characterization, and anticancer efficacy in lung cancer cells with protective effects in Caenorhabditis elegans

Nano TransMed
This study explores the synthesis, characterization, and biomedical applications of silver nanoparticles (AgNPs) synthesized using Simarouba glauca leaf extract.
Santosh Mallikarjun Bhavi, Akshata Choudhari Padti, Bothe Thokchom, Sapam Riches Singh, Shivanand S. Bhat, Sukesh Kumar Bajire, Rajesh P. Shastry, B.S. Srinath, Sushma Subraya Gummani, B.P. Harini, Ramesh Babu Yarajarla   +10 more
doaj   +1 more source

TBC1D22B Regulates ER‐to‐Golgi Trafficking via RAB1B Inactivation and Promotes Oncogenic Programs in Breast Cancer

Advanced Science, EarlyView.
TBC1D22B, a Golgi‐localized RabGAP linked to poor prognosis in breast cancer, inhibits ER‐to‐Golgi transport via RAB1B inactivation. This disrupts secretion, drives oncogenic transcriptional reprogramming, and promotes tumor growth. These findings indicate that TBC1D22B connects membrane trafficking to transcriptional control and cancer progression ...
Flavia Martino, Mariadomenica Lupi, Alessandra Murabito, Fabio Bedin, Giulia Villari, Linda Andreoli, Stefano Freddi, Bronislava Matoskova, Rosa Pennisi, Stella Fontana, Amir Fardin, Gaelle Boncompain, Franck Perez, Federico Bussolino, Alessandro Cuomo, Sara Sigismund, Letizia Lanzetti   +16 more
wiley   +1 more source