Results 101 to 110 of about 641,541 (231)

Rate and cost of adaptation in the Drosophila Genome [PDF]

open access: yesarXiv, 2014
Recent studies have consistently inferred high rates of adaptive molecular evolution between Drosophila species. At the same time, the Drosophila genome evolves under different rates of recombination, which results in partial genetic linkage between alleles at neighboring genomic loci. Here we analyze how linkage correlations affect adaptive evolution.
arxiv  

Effect of Itrifal Muqawwi-e-Dimagh (a polyherbal drug) on the transgenic Drosophila model of Parkinson's Disease

open access: yesPhytomedicine Plus, 2021
Background: Parkinson's Disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the mid brain which leads to the depletion of dopamine levels.
Yasir Hasan Siddique   +4 more
doaj  

In the quest for the ideal sweetener: Aspartame exacerbates selected biomarkers in the fruit fly (Drosophila melanogaster) model of Alzheimer's disease more than sucrose

open access: yesAging Brain, 2023
This study evaluated the effect of dietary inclusions of aspartame and sucrose on some selected behavioral and biochemical indices linked with Alzheimer's disease in a transgenic fruit fly (Drosophila melanogaster) model expressing human amyloid ...
Bukola Christiana Adedayo   +3 more
doaj  

Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration [PDF]

open access: yes, 2017
Endoribonucleases participate in almost every step of eukaryotic RNA metabolism, acting either as degradative or biosynthetic enzymes. We previously identified the founding member of the Eukaryotic EndoU ribonuclease family, whose components display ...
BOZZONI, Irene   +11 more
core   +1 more source

RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2. [PDF]

open access: yes, 2020
Polycomb Group (PcG) proteins form memory of transient transcriptional repression that is necessary for development. In Drosophila, DNA elements termed Polycomb Response Elements (PREs) recruit PcG proteins.
Alecki, Célia   +8 more
core  

Cluster partitions and fitness landscapes of the Drosophila fly microbiome [PDF]

open access: yesarXiv, 2018
Beerenwinkel et al.(2007) suggested studying fitness landscapes via regular subdivisions of convex polytopes. Building on their approach we propose cluster partitions and cluster filtrations of fitness landscapes as a new mathematical tool. In this way, we provide a concise combinatorial way of processing metric information from epistatic interactions.
arxiv  

THEWILLISTONIGROUP OF SIBLING SPECIES OFDROSOPHILA [PDF]

open access: bronze, 1949
H. Burla   +5 more
openalex   +1 more source

Paralog Explorer: A resource for mining information about paralogs in common research organisms

open access: yesComputational and Structural Biotechnology Journal, 2022
Paralogs are genes which arose via gene duplication, and when such paralogs retain overlapping or redundant function, this poses a challenge to functional genetics research.
Yanhui Hu   +5 more
doaj  

Polytene chromosomes as indicators of phylogeny in several species groups of Drosophila. [PDF]

open access: yes, 2001
BackgroundPolytene chromosome banding patterns have long been used by Drosophila evolutionists to infer degree of relatedness among taxa. Recently, nucleotide sequences have preempted this traditional method.
Baker, RH   +4 more
core  

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