Results 121 to 130 of about 407,893 (313)

In Silico evaluation of phytoconstituents from Carica Papaya and its anti-hyperglycemic activities on high sucrose-induced oxidative stress in Drosophila melanogaster

Scientific Reports
Oxidative stress plays a key role in the development of metabolic disorders, such as diabetes. This study investigated the phytoconstituents present in Carica papaya (AECP) using an in silico model, and its anti-hyperglycemic activities on high sucrose ...
Omotade I. Oloyede, Seun J. Ibrahim, Scholastica O. Anadozie, Erdi C. Aytar, Oluwole B. Akawa, Isaac A. Adu, Oluwadunsin S. Omodaratan, Olabisi T. Obafemi, Olusola B. Adewale   +8 more
doaj   +1 more source

Global Patterns of Tissue-Specific Alternative Polyadenylation in Drosophila [PDF]

, 2013
Peter Smibert, Pedro Miura, Jakub Orzechowski Westholm, Sol Shenker, Gemma E. May, Michael O. Duff, Dayu Zhang, Brian D. Eads, Joe Carlson, James Brown, Robert C. Eisman, Justen Andrews, Thomas C. Kaufman, Peter Cherbas, S Celniker, Brenton R. Graveley, Eric C. Lai   +16 more
openalex   +1 more source

Polyphenol diet and exercise as neuroprotective factors in a Drosophila model of Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
Moderate exercise and low‐dose ellagic acid supplementation improved motor performance, learning, and longevity in a transgenic Drosophila model of Alzheimer's disease. Both interventions showed hormetic effects—that is, beneficial at low levels, but detrimental at higher intensities or doses.
Michelle Morgan, Zaida Lopez Rodriguez, Richard E. Hartman   +2 more
wiley   +1 more source

FlyExpress 7: An Integrated Discovery Platform To Study Coexpressed Genes Usingin SituHybridization Images inDrosophila [PDF]

, 2017
Sudhir Kumar, Charlotte E. Konikoff, Maxwell Sanderford, Li Liu, Stuart J. Newfeld, Jieping Ye, Rob J. Kulathinal   +6 more
openalex   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

VIABILITY INTERACTIONS, IN VIVO ACTIVITY AND THE G6PD POLYMORPHISM IN DROSOPHILA MELANOGASTER [PDF]

, 1984
Walter F. Eanes
openalex   +1 more source

Divergence of the yellow Gene Between Drosophila melanogaster and D. subobscura: Recombination Rate, Codon Bias and Synonymous Substitutions [PDF]

, 1997
Agustí Munté, Montserrat Aguadé, Carmen Segarra   +2 more
openalex   +1 more source

Coleopteran-specific StaufenC functions like Drosophila melanogaster Loquacious-PD in dsRNA processing [PDF]

, 2021
Kyungbo Kim, Jinmo Koo, June‐Sun Yoon, Subba Reddy Palli   +3 more
openalex   +1 more source

Non‐Synaptic Function and Localization of Syntaxin‐Binding Protein 1 in a Mouse Model of STXBP1‐Related Epileptic Encephalopathy

Annals of Neurology, EarlyView.
Objective De novo mutations in the syntaxin‐binding protein 1 (STXBP1), encoded by STXBP1, are among the most prevalent causes of variable neurodevelopmental disorders, including epileptic encephalopathy, developmental delay, and movement disorders.
Tao Yang, Rajat Banerjee, Yamei Deng, Sheetal Jahagirdar1, Alexey I. Nesvizhskii, Michael D. Uhler, Jack M. Parent, Yu Wang   +7 more
wiley   +1 more source

Experimental and computational insights into the therapeutic mechanisms of resveratrol in a Drosophila α-synuclein model of Parkinson’s disease

Scientific Reports
Parkinson’s disease (PD) is a multifactorial neurodegenerative disorder driven by genetic predisposition and environmental exposure. Given its well-documented antioxidative and neuroprotective properties, resveratrol is increasingly being considered for ...
Amos Olalekan Abolaji, Adeola Oluwatosin Adedara, Judith Chizoba Madu, Oluwabunmi Tomilola Owalude, Oludare Michael Ogunyemi, Damilola A. Omoboyowa, Folorunsho Bright Omage, Alexander J. Whitworth, Michael Aschner   +8 more
doaj   +1 more source