Results 121 to 130 of about 842,087 (402)

Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo. [PDF]

open access: yes, 1989
We have developed affinity chromatography methods for the isolation of microtubule-associated proteins (MAPs) from soluble cytoplasmic extracts and have used them to analyze the cytoskeleton of the early Drosophila embryo.
Alberts, BM, Field, CM, Kellogg, DR
core  

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li   +15 more
wiley   +1 more source

Effect of bromocriptine alginate nanocomposite (BANC) on a transgenic Drosophila model of Parkinson's disease

open access: yesDisease Models & Mechanisms, 2016
The effect of bromocriptine, a dopamine agonist, administered in the form of bromocriptine alginate nanocomposite (BANC) was studied on Parkinson's disease (PD) model flies.
Yasir Hasan Siddique   +9 more
doaj   +1 more source

Collective mechanics of embryogenesis: Formation of ventral furrow in Drosophila [PDF]

open access: yesarXiv, 2011
We propose a 2D mechanical model of the ventral furrow formation in Drosophila that is based on undifferentiated epithelial cells of identical properties whose energy resides in their membrane. Depending on the relative tensions of the apical, basal, and lateral sides, the minimal-energy states of the embryo cross-section includes circular, elliptical,
arxiv  

Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila

open access: yeseLife, 2018
Mutations in the genes for PINK1 and parkin cause Parkinson’s disease. PINK1 and parkin cooperate in the selective autophagic degradation of damaged mitochondria (mitophagy) in cultured cells.
Tom Cornelissen   +5 more
semanticscholar   +1 more source

Drosophila nuclear lamin precursor Dm0 is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene. [PDF]

open access: yes, 1988
A cDNA clone encoding a portion of Drosophila nuclear lamins Dm1 and Dm2 has been identified by screening a lambda-gt11 cDNA expression library using Drosophila lamin-specific monoclonal antibodies.
Bare, JW   +9 more
core   +1 more source

Drosophilidae (Diptera) Collected in Spring in Michigan [PDF]

open access: yes, 2017
Drosophilids in mid-Michigan overwinter in a preadult stage. One hun- dred twenty-two individuals (84 f, 38 m) representing 14 species were collected over bait in April and May 1992. All appeared recently emerged and had entire wings.
Band, Henretta Trent
core   +3 more sources

Drosophila (Drosophila) immigrans Sturtevant 1921

open access: yes, 2023
Published as part of Gornostaev, N. G. & Lyupina, Yu. V., 2023, An annotated list of the drosophilid flies (Diptera: Drosophilidae) of the Republic of Adygea, pp.
Gornostaev, N. G., Lyupina, Yu. V.
openaire   +2 more sources

Machine Learning‐Based Wind Classification by Wing Deformation in Biomimetic Flapping Robots: Biomimetic Flexible Structures Improve Wind Sensing

open access: yesAdvanced Intelligent Systems, EarlyView.
Strain gauges are attached to biomimetic flapping wings to investigate how wing strain sensors detect wind directions. A convolutional neural network model for wind direction classification is developed through experiments. The results reveal that wind classification is possible with strain data of only 0.2 flapping cycles, and the use of biomimetic ...
Kenta Kubota, Hiroto Tanaka
wiley   +1 more source

On a Hyperbolic-Parabolic Parasitoid-Parasite System: Well Posedness and Control [PDF]

open access: yesarXiv, 2020
We develop a time and space dependent predator-prey model. The predators' equation is a non local hyperbolic balance law, while the diffusion of prey obeys a parabolic equation, so that predators "hunt" for prey, while prey diffuse. A control term allows to describe the use of predators as parasitoids to limit the growth of prey-parasites.
arxiv  

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