Results 171 to 180 of about 407,893 (313)

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

Cytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli, Preet Patel, Aneri Shethji, David Gau   +3 more
wiley   +1 more source

JAK-STAT pathway activation compromises nephrocyte function in a <i>Drosophila</i> high-fat diet model of chronic kidney disease. [PDF]

Elife
Zhao Y, Duan J, Seah H, van de Leemput J, Han Z.   +4 more
europepmc   +1 more source

Genetic variation and the ecological parameter 'food medium' in cage populations of Drosophila melanogaster.

, 1976
S. Alahiotis
openalex   +1 more source

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

Developmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez, Niusha Banoukh, Fiona Mensching, Robert V. Skibbens, M. Kathryn Iovine   +4 more
wiley   +1 more source

Maintaining sexual identity in adult flies is an ongoing commitment. [PDF]

PLoS Biol
Kopp A.
europepmc   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

Developmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim, You‐Lim Hwang, Sunwoo Yeom, Seung‐Hae Kwon, Sang‐Hak Jeon   +4 more
wiley   +1 more source

FlyDEGdb knowledge base on differentially expressed genes of Drosophila melanogaster, a model object in biomedicine. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Podkolodnaya OA, Deryuzhenko MA, Tverdokhleb NN, Zolotareva KA, Makovka YV, Podkolodny NL, Suslov VV, Chadaeva IV, Fedoseeva LA, Seryapina AA, Oshchepkov DY, Bogomolov AG, Kondratyuk EY, Redina OE, Markel AL, Gruntenko NE, Ponomarenko MP.   +16 more
europepmc   +1 more source

Decision letter: Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors

, 2014

openalex   +1 more source

Effects of developmental plasticity on heat tolerance may be mediated by changes in cell size in Drosophila melanogaster [PDF]

, 2019
Nadja Verspagen, Félix P. Leiva, Irene M. Janssen, Wilco C. E. P. Verberk   +3 more
openalex   +1 more source

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

Developmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe, Yu Chen, Geoff Shaw, Marilyn B. Renfree   +3 more
wiley   +1 more source