Results 171 to 180 of about 913,402 (352)

The Lysine Demethylase dKDM2 Is Non-essential for Viability, but Regulates Circadian Rhythms in Drosophila

open access: gold, 2018
Yani Zheng   +9 more
openalex   +1 more source

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

open access: yesAdvanced Science, EarlyView.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source

Experimental and computational insights into the therapeutic mechanisms of resveratrol in a Drosophila α-synuclein model of Parkinson’s disease

open access: yesScientific Reports
Parkinson’s disease (PD) is a multifactorial neurodegenerative disorder driven by genetic predisposition and environmental exposure. Given its well-documented antioxidative and neuroprotective properties, resveratrol is increasingly being considered for ...
Amos Olalekan Abolaji   +8 more
doaj   +1 more source

The goddard and saturn genes are essential for Drosophila male fertility and may have arisen de novo [PDF]

open access: bronze, 2017
Anna M. Gubala   +6 more
openalex   +1 more source

Role of the Forkhead Transcription Factors Fd4 and Fd5 During Drosophila Leg Development

open access: gold, 2021
Mireya Ruiz-Losada   +2 more
openalex   +1 more source

The Genetics and Biology of Drosophila

open access: yesHeredity, 1976
M. Ashburner   +4 more
semanticscholar   +1 more source

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

open access: yesAdvanced Science, EarlyView.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu   +13 more
wiley   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Accelerating Pinned Insect Specimen Digitization: A Deep Learning Pipeline for Future Collaborative Robots

open access: yesAdvanced Intelligent Systems, EarlyView.
The study presents a prototype novel workflow that utilizes artificial intelligence for the digitization of natural history collections, which would fit within a robotic‐integrated system. The work focuses on a collaborative‐robot (cobot) inspired workflow to digitize one of the largest collections housed at the Natural History Museum UK: pinned ...
Naifeng Zhang   +4 more
wiley   +1 more source

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