Results 191 to 200 of about 407,893 (313)

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Shaker potassium channel mediates an age-sensitive neurocardiac axis regulating sleep and cardiac function in Drosophila. [PDF]

Biogerontology
Madamanchi K, Bannister D, Docuyanan A, Bhide S, Melkani GC.   +4 more
europepmc   +1 more source

Long‐Term Maintenance of Complex Chromosomal Inversion Polymorphism in Drosophila mediopunctata [PDF]

Fabiana Uno, Felipe Bastos Rocha, Louis Bernard Klaczko   +2 more
openalex   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Comparative functional and evolutionary analysis of essential germline stem cell genes across the genus Drosophila and two outgroup species. [PDF]

G3 (Bethesda)
Arnce LR, Bubnell JE, Aquadro CF.
europepmc   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Genetic evaluation of CRISPR-Cas9 off-target effects from deleterious mutations on Drosophila male single X chromosome. [PDF]

Funct Integr Genomics
Bian W, Mcquarrie DWJ, Haussmann IU, Arnold R, Soller M.   +4 more
europepmc   +1 more source

A Single NPFR Neuropeptide F Receptor Neuron That Regulates Thirst Behaviors in Drosophila [PDF]

Delia Ramírez, Brian P Wang, Dan Landayan, Gagandeep Kaur, Fred W. Wolf   +4 more
openalex   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

Why just fly? [PDF]

Fly (Austin)
Dearden PK.
europepmc   +1 more source