Results 331 to 340 of about 5,995,584 (403)

Metformin and Dietary Restriction Counteract Aging via Reducing m6A–Dependent Stabilization of Methionine Synthase mRNA in Brachionus asplanchnoidis (Rotifera)

open access: yesAging Cell, EarlyView.
Metformin and dietary restriction modulate m6A to extend lifespan of rotifer, highlighting MTR as a central regulator of aging through methionine metabolism. ABSTRACT Metformin, a medication primarily used to treat diabetes, has gained attentions for its potential antiaging properties.
Yu Zhang   +8 more
wiley   +1 more source

Rapamycin, Not Metformin, Mirrors Dietary Restriction‐Driven Lifespan Extension in Vertebrates: A Meta‐Analysis

open access: yesAging Cell, EarlyView.
The authors provide evidence that, together with Dietary Restriction, Rapamcyin and not Metformin, provides a significant lifespan extension in vertebrates. ABSTRACT Dietary restriction (DR) robustly increases lifespan across taxa. However, in humans, long‐term DR is difficult to maintain, leading to the search for compounds that regulate metabolism ...
Edward R. Ivimey‐Cook   +2 more
wiley   +1 more source

Myosin VI is expressed in developing ovarian follicles in <i>Drosophila</i> but is not essential for effective oogenesis. [PDF]

open access: yesFront Cell Dev Biol
Lenartowski R   +8 more
europepmc   +1 more source

The Drosophila nucleoporin ELYS is required for parental chromosome arrangement at fertilization. [PDF]

open access: yesG3 (Bethesda)
Hirai K   +7 more
europepmc   +1 more source

A temporally restricted function of the dopamine receptor Dop1R2 during memory formation. [PDF]

open access: yesElife
Kaldun JC   +5 more
europepmc   +1 more source

Synergistic DNA and RNA binding of the Hox transcription factor Ultrabithorax coordinates splicing and shapes in vivo homeotic functions. [PDF]

open access: yesNucleic Acids Res
Blanco C   +8 more
europepmc   +1 more source

Gene model for the ortholog of <i>Ilp3</i> in <i>Drosophila ananassae</i>. [PDF]

open access: yesMicroPubl Biol
Gruys ML   +12 more
europepmc   +1 more source

Spermidine supplementation and protein restriction protect from organismal and brain aging independently. [PDF]

open access: yesAging (Albany NY)
Liang Y   +7 more
europepmc   +1 more source

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