Zinc finger binding motifs do not explain recombination rate variation within or between species of Drosophila. [PDF]
PLoS ONE, 2012 In humans and mice, the Cys(2)His(2) zinc finger protein PRDM9 binds to a DNA sequence motif enriched in hotspots of recombination, possibly modifying nucleosomes, and recruiting recombination machinery to initiate Double Strand Breaks (DSBs).
Caiti S S Heil, Mohamed A F Noor
doaj +1 more source
In vivo RNAi rescue in Drosophila melanogaster with genomic transgenes from Drosophila pseudoobscura. [PDF]
PLoS ONE, 2010 BACKGROUND: Systematic, large-scale RNA interference (RNAi) approaches are very valuable to systematically investigate biological processes in cell culture or in tissues of organisms such as Drosophila.
Christoph C H Langer +4 more
doaj +1 more source
Odorant receptor (Or) genes: polymorphism and divergence in the D. melanogaster and D. pseudoobscura lineages. [PDF]
PLoS ONE, 2010 BACKGROUND: In insects, like in most invertebrates, olfaction is the principal sensory modality, which provides animals with essential information for survival and reproduction.
Inês C Conceição, Montserrat Aguadé
doaj +1 more source
An Improved Method for Identification of Pre-miRNA in
IEEE Access, 2020 Identification of microRNAs is important in studies of regulation of gene expression in many biologyical processes. In this study, we developed an improved method for identification of microRNAs in Drosophila.
Tieying Yu, Min Chen, Chunde Wang
doaj +1 more source
An investigation of Y chromosome incorporations in 400 species of Drosophila and related genera. [PDF]
PLoS Genetics, 2018 Y chromosomes are widely believed to evolve from a normal autosome through a process of massive gene loss (with preservation of some male genes), shaped by sex-antagonistic selection and complemented by occasional gains of male-related genes.
Eduardo G Dupim +10 more
doaj +1 more source
Genetics, 2020 The Drosophila pseudoobscura Sex-Ratio (SR) chromosome was one of the first-discovered segregation distorter chromosomes. Despite being a historically significant and well-studied segregation distortion system, the mechanisms allowing for the long-term...
Zachary L. Fuller +8 more
semanticscholar +1 more source
Ancestral polymorphisms explain the role of chromosomal inversions in speciation. [PDF]
PLoS Genetics, 2018 Understanding the role of chromosomal inversions in speciation is a fundamental problem in evolutionary genetics. Here, we perform a comprehensive reconstruction of the evolutionary histories of the chromosomal inversions in Drosophila persimilis and D ...
Zachary L Fuller +4 more
doaj +1 more source
Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3 [PDF]
, 2009 Background: Alternative splicing (AS) of maturing mRNA can generate structurally and functionally distinct transcripts from the same gene. Recent bioinformatic analyses of available genome databases inferred a positive correlation between intron length ...
A Marchler-Bauer +100 more
core +5 more sources
Functional Evolution of a cis-Regulatory Module [PDF]
, 2005 Lack of knowledge about how regulatory regions evolve in relation to their structure–function may limit the utility of comparative sequence analysis in deciphering cis-regulatory sequences.
Alekseeva, Elena +5 more
core +9 more sources
How chromosomal inversions reorient the evolutionary process
Journal of Evolutionary Biology, Volume 36, Issue 12, Page 1761-1782, December 2023., 2023 Inversions often play key roles in adaptation and speciation, but the processes that direct their evolution are obscured by the characteristic that makes them so unique (reduced recombination between arrangements). In this review, we examine how different mechanisms can impact inversion evolution, weaving together both theoretical and empirical studies.
Emma L. Berdan +18 more
wiley +1 more source