Results 51 to 60 of about 21,709 (255)
Abstract Objective This study was undertaken to evaluate the efficacy and safety of deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) compared with best medical treatment (BMT) in patients with drug‐resistant epilepsy (DRE).
Stéphan Chabardès +30 more
wiley +1 more source
Characteristics of unintentional drowning deaths in children with autism spectrum disorder
Background The reported prevalence of autism spectrum disorder (ASD) has increased markedly in the past two decades. Recent research indicates that children with ASD are at a substantially increased risk of injury mortality, particularly from ...
Joseph Guan, Guohua Li
doaj +1 more source
Does having bad epilepsy make you a good surgical candidate? A number needed to treat analysis
Abstract Epilepsy surgery is an established treatment for drug‐resistant epilepsy, offering a realistic prospect of seizure freedom in well‐selected candidates. However, surgery is sometimes offered to individuals with a low probability of seizure freedom when it is framed as potentially “life‐saving” on the basis of the elevated mortality associated ...
Sallie Baxendale +2 more
wiley +1 more source
Parents despite support networks? An intersectional analysis of disabled parenthood
Abstract This article uses an intersectional perspective that considers patriarchal and ableist mandates to understand how family and professional support networks impact the reproductive trajectories of disabled people. The study analyzes 16 semi‐structured interviews with disabled people and 1 with a non‐disabled support worker.
Laura Sanmiquel‐Molinero +2 more
wiley +1 more source
Abstract Introduction Suicide is a significant public health concern and the second leading cause of death in adolescents and young adults. This study sought to better understand differences in demographic and clinical characteristics of young people who attempted suicide during three phases of this developmental period: late adolescence (14–17 years),
Nicholas M. Brdar +7 more
wiley +1 more source
ABSTRACT Employees in highly demanding, interdependent work environments face a dilemma: while avoidance‐focused job crafting can preserve their own well‐being, these self‐initiated changes to their jobs could negatively affect coworkers. Drawing on qualitative interviews with 81 employees concurrently working for multiple agile teams in a European ...
Helene Tenzer +4 more
wiley +1 more source
Ion Activation Methods for Top‐Down Proteomics
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Noise, Hearing, and Communication in the Operating Room: A Mixed‐Methods Study
Abstract Objective To evaluate noise‐related communication barriers in the operating room and to identify strategies for overcoming them. Study Design Cross‐sectional mixed‐methods survey. Setting Tertiary academic medical center. Methods An anonymous 21‐item electronic survey was distributed to operating room personnel, including surgeons ...
Sarah E. Hughes +9 more
wiley +1 more source
Socio-Structural Factors as Predictors of Parents' Intentions to Enrol Their Children in Swimming Lessons. [PDF]
ABSTRACT Issue Addressed Swimming lessons are an effective drowning prevention strategy, yet uptake remains socially patterned. Socio‐structural factors such as parent age, sex and family income may shape parents' decisions to enrol their children in swimming lessons.
Hamilton K +5 more
europepmc +2 more sources

