Results 71 to 80 of about 100,447 (280)

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

British Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia, Huang Xingxing, Jin Lu, Wang Ruwei   +3 more
wiley   +1 more source

Quality of Postoperative Pain Management after Midfacial Fracture Repair—An Outcome-oriented Study [PDF]

, 2015
Objectives There is a lack of literature regarding the procedure-specific quality of acute postoperative pain management after midfacial fracture repair.
Djedovic, Gabriel, Gomez-Dammeier, Marta, Guentsch, Arndt, Meissner, Winfried, Peisker, Andre, Raschke, Gregor F., Rieger, Ulrich M., Schaefer, Oliver, Venth, Eric   +8 more
core   +2 more sources

Video surveillance for monitoring driver's fatigue and distraction [PDF]

, 2012
Fatigue and distraction effects in drivers represent a great risk for road safety. For both types of driver behavior problems, image analysis of eyes, mouth and head movements gives valuable information.
Grisales, Victor, Jimenez Moreno, Robinson, Orjuela Vargas, Sergio Alejandro, Philips, Wilfried, Prieto, Flavio, Van Hese, Peter   +5 more
core   +2 more sources

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko, Titiaan E. Post, Pamela K. Strugala, Erica S. Klaassen, Linda E. Klumpers, Saco J. de Visser, Cristina Sempio, Jost Klawitter, Jules A. A. C. Heuberger, Geert J. Groeneveld   +9 more
wiley   +1 more source

Re-examination of Oostenbroek et al. (2016): evidence for neonatal imitation of tongue protrusion [PDF]

, 2017
The meaning, mechanism, and function of imitation in early infancy have been actively discussed since Meltzoff and Moore's (1977) report of facial and manual imitation by human neonates. Oostenbroek et al. (2016) claim to challenge the existence of early
Anisfeld, Aslin, Brazelton, Cohen, Coulon, Farroni, Ferrari, Heimann, Hofsten, Hofsten, Hofsten, Kent, Lieberman, Marshall, Marshall, Meltzoff, Meltzoff, Meltzoff, Meltzoff, Meltzoff, Meltzoff, Meltzoff, Messinger, Murray, Nagy, Nagy, Oostenbroek, Piaget, Previc, Ruff, Simpson, Simpson, Soussignan, Tronick, Valenza   +34 more
core   +5 more sources

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

A Review of the Studies on Driver Drowsiness Detection Sensors and Proposing Hybrid Diagnostic Methods and Efficient Model Design

بهداشت و ایمنی کار, 2023
Introduction: In recent years, driver’s drowsiness has been one of the leading causes of road accidents, which can lead to physical injuries, death, and significant economic losses.
Naser Nik Afshar, Mostafa Kamali, Elham Aklaghi Pirposhteh, Hesamedin Askai Majabadi, Nasir Amanat, Mohsen Poursadeqiyan   +5 more
doaj  

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

RESEARCH ON DEVELOPING A MONITORING SYSTEM FOR DROWSINESS DETECTION BASED ON COMPUTER VISION

Tạp chí Khoa học
This article focuses on the research and development of a model for a drowsiness detection and monitoring system while driving based on computer vision. The product can be applied to current vehicles (such as cars or vehicles with similar functions). The
Dien Thi Hong Ha
doaj   +1 more source

Real-Time System for Driver Fatigue Detection Based on a Recurrent Neuronal Network

Journal of Imaging, 2020
In recent years, the rise of car accident fatalities has grown significantly around the world. Hence, road security has become a global concern and a challenging problem that needs to be solved.
Younes Ed-Doughmi, Najlae Idrissi, Youssef Hbali   +2 more
doaj   +1 more source