Results 1 to 10 of about 4,116,904 (269)
Frontiers in Pharmacology, 2021 There are currently no licensed drugs against porcine epidemic diarrhea virus (PEDV), but vaccines are available. We identified a natural molecule, epigallocatechin-3-gallate (EGCG), the main polyphenol in green tea, which is effective against infection ...
Changchao Huan +22 more
doaj +1 more source
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
Frontiers in Genetics, 2021 Drug repositioning is an application-based solution based on mining existing drugs to find new targets, quickly discovering new drug-disease associations, and reducing the risk of drug discovery in traditional medicine and biology.
Bo-Wei Zhao +13 more
doaj +1 more source
Drug Selection via Joint Push and Learning to Rank [PDF]
IEEE/ACM Transactions on Computational Biology and Bioinformatics
( Volume: 17, Issue: 1, 01 Jan.-Feb. 2020), 2018 Selecting the right drugs for the right patients is a primary goal of precision medicine. In this manuscript, we consider the problem of cancer drug selection in a learning-to-rank framework. We have formulated the cancer drug selection problem as to accurately predicting 1). the ranking positions of sensitive drugs and 2).
arxiv +1 more source
Songklanakarin Journal of Science and Technology (SJST), 2022 The present review discusses the effects of pharmaceutical drugs on aquatic ecosystem, in particular the fish to be precise. The focus is on roles of multiple drug types like antimicrobial, antipsychotic, analgesic, and anti-inflammatory; and the ...
Drugs and Fish
doaj +1 more source
Hyperbolic Molecular Representation Learning for Drug Repositioning [PDF]
arXiv, 2022 Learning accurate drug representations is essential for task such as computational drug repositioning. A drug hierarchy is a valuable source that encodes knowledge of relations among drugs in a tree-like structure where drugs that act on the same organs, treat the same disease, or bind to the same biological target are grouped together.
arxiv
Frontiers in Veterinary Science, 2021 Canine malignant mammary tumor is a dangerously fatal neoplastic disease with poor survival in female dogs. The aim of this study was to preliminary characterize a novel canine mammary cancer cell line, B-CMT, from canine primary mammary gland tumor, and
Rifei Li +6 more
doaj +1 more source
The relationship between trait emotional intelligence and problematic alcohol use among college students [PDF]
Health Promotion Perspectives, 2022 Background: Problematic alcohol use among college students is a significant public health concern. Emotional intelligence (EI), or the ability to detect one’s own and others’ emotions and to use this information to direct behavior, is suggested to ...
Robert E Davis +4 more
doaj +1 more source
AMFPMC -- An improved method of detecting multiple types of drug-drug interactions using only known drug-drug interactions [PDF]
arXiv, 2023 Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is essential, however it is costly and time-consuming.
arxiv
Frontiers in Pharmacology, 2021 Traditional methods to standardize exposures in pharmacoepidemiologic studies, like defined daily-doses, may be inadequate to capture drug class effects when there are many in-class medications, formulations, and administration routes.
Kaleen N. Hayes +8 more
doaj +1 more source
NeuroCADR: Drug Repurposing to Reveal Novel Anti-Epileptic Drug Candidates Through an Integrated Computational Approach [PDF]
arXiv, 2023 Drug repurposing is an emerging approach for drug discovery involving the reassignment of existing drugs for novel purposes. An alternative to the traditional de novo process of drug development, repurposed drugs are faster, cheaper, and less failure prone than drugs developed from traditional methods.
arxiv