Results 1 to 10 of about 7,733,316 (205)

Drugging Drug Resistance [PDF]

Cell, 2010
Resistance to anticancer drugs is widely observed in vitro and in cancer patients, but its prevalence is too high to be solely explained by the acquisition of mutations. Sharma et al. (2010) now report that dynamic chromatin modifications may be an independent route to drug resistance in cancer cells that can be reversed by epigenetic drugs.
Dannenberg, Jan-Hermen, Berns, Anton
openaire   +2 more sources

NOACs: drug–drug interactions [PDF]

Canadian Medical Association Journal, 2016
We commend Fralick and colleagues for their article on drug interactions with rivaroxaban.[1][1] All novel oral anticoagulants (NOACs) were introduced as at least noninferior (in some cases superior) to warfarin.
Bartosz, Hudzik, Andrzej, Lekston, Mariusz, Gasior   +2 more
openaire   +2 more sources

Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-Naïve chronic HBV patients [PDF]

, 2013
Background: Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, the development of drug resistance is a major limitation to their long-term effectiveness.
Abedi, F., Alavian, S.M., Ataei, B., Azad, T.M., Daram, M., Fazeli, Z., Ghamari, S., Goodarzi, Z., Jazayeri, S.M., Judaki, M.A., Kalantari, E., Karimzadeh, H., Keyvani, H., Khedive, A., Mahabadi, M., Mahmoodi, M., Malekzadeh, R., Mansour-Ghanaei, F., Montazeri, G., Moradi, A., Nejatizadeh, A., Norouzi, M., Pourhosseingholi, M.A., Rafatpanah, H., Ramezani, F., Saberfar, E., Saberfiroozi, M., Samimirad, K., Sanei-Moghaddam, I., Sarizadeh, G., Sayad, B., Somi, M.H., Yaran, M., Ziee, M.   +33 more
core   +1 more source

Detecting a signal in the noise : Monitoring the global spread of novel psychoactive substances using media and other open source information [PDF]

, 2015
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no ...
Canadian Community Epidemiology Network On Drug Use, Center for Substance Abuse Research, European Monitoring Centre For Drugs And Drug Addiction, Sumnall H   +3 more
core   +1 more source

Adverse reactions of amiodarone [PDF]

, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo, Ciacciarelli, Marco, Colunga Biancatelli, Ruben Ml, Congedo, Viviana, Iuliano, Luigi, Polidoro, Alessandro   +5 more
core   +1 more source

Strategy for applying utility model patents in clinical nursing (临床护理用具实用新型专利申请心得体会)

中西医结合护理, 2021
This paper summarized the strategy for applying utility model patents in clinical nursing. Issues about meaning of patent, application procedure and design inspiration were discussed and shared, in order to provide reference in design and application of ...
QIAO Shouang (乔首昂), WANG Shuo (王烁), PEI Xiaolu (裴晓璐)   +2 more
doaj   +1 more source

Drug-Drug Interaction of Antifungal Drugs

YAKUGAKU ZASSHI, 2005
This article reviews the in vitro metabolic and the in vivo pharmacokinetic drug-drug interactions with antifungal drugs, including fluconazole, itraconazole, micafungin, miconazole, and voriconazole. In the in vitro interaction studies, the effects of antifungal drugs on specific activities of cytochrome P450s (CYPs), including CYP1A2, CYP2C9, CYP2C19,
Toshiro, Niwa, Toshifumi, Shiraga, Akira, Takagi   +2 more
openaire   +3 more sources

Pharmacodynamic Drug–Drug Interactions [PDF]

Clinical Pharmacology & Therapeutics, 2019
Pharmacodynamic drug–drug interactions (DDIs) occur when the pharmacological effect of one drug is altered by that of another drug in a combination regimen. DDIs often are classified as synergistic, additive, or antagonistic in nature, albeit these terms are frequently misused.
Jin, Niu, Robert M, Straubinger, Donald E, Mager   +2 more
openaire   +2 more sources

Changes in prescription drug abuse during the COVID-19 pandemic evidenced in the Catalan pharmacies

Frontiers in Public Health, 2023
IntroductionThe impact of a pandemic on the mental health of the population is to be expected due to risk factors such as social isolation. Prescription drug abuse and misuse could be an indicator of the impact of the COVID-19 pandemic on mental health ...
Maria Perelló, Maria Perelló, Karla Rio-Aige, Karla Rio-Aige, Pilar Rius, Guillermo Bagaría, Anna M. Jambrina, Anna M. Jambrina, Montse Gironès, Francisco José Pérez-Cano, Francisco José Pérez-Cano, Manel Rabanal, Manel Rabanal, Manel Rabanal   +13 more
doaj   +1 more source

Legal and illegal drug use among female sex workers in bar and club prostitution in Belgium: a quantitative and qualitative study [PDF]

, 2013
Aims: This study describes the amounts and effects of drug use in bar and club sex work, and the use of healthcare for the drug-related needs of sex workers (SW). Methods: A cross-sectional study was carried out in Belgium.
Decorte, Tom, Leuridan, Elke, Van Damme, Pierre, Van Hal, Guido, Van Nunen, Karolien   +4 more
core   +1 more source