Results 1 to 10 of about 414,632 (61)

Creating Data Standards to Support the Electronic Transmission of Compounded Nonsterile Preparations (CNSPs): Perspectives of a United States Pharmacopeia Expert Panel

Children, 2022
The perspectives of the Compounded Drug Preparation Information Exchange Expert Panel of the United States Pharmacopeia (CDPIE-EP) on the urgent need to create and maintain data standards to support the electronic transmission of an interoperable dataset
Richard H. Parrish, Scott Ciarkowski, David Aguero, Sandra Benavides, Donna Z. Bohannon, Roy Guharoy, on behalf of the United States Pharmacopeia Compounded Drug Preparation Information Exchange Expert Panel   +6 more
doaj   +1 more source

Plant Antimicrobial Peptides (PAMPs): Features, Applications, Production, Expression, and Challenges

Molecules, 2022
The quest for an extraordinary array of defense strategies is imperative to reduce the challenges of microbial attacks on plants and animals. Plant antimicrobial peptides (PAMPs) are a subset of antimicrobial peptides (AMPs). PAMPs elicit defense against
Olalekan Olanrewaju Bakare, Arun Gokul, Adewale Oluwaseun Fadaka, Ruomou Wu, Lee-Ann Niekerk, Adele Mariska Barker, Marshall Keyster, Ashwil Klein   +7 more
doaj   +1 more source

Off-label and unlicensed drug treatments in Neonatal Intensive Care Units: a systematic review

Journal of Pediatric and Neonatal Individualized Medicine, 2021
Newborns are particularly susceptible to off-label and unlicensed (OLUL) drug treatments, especially in the intensive care setting, inferring from dosing regimens and indications supported in older populations and built on non-neonatal pathophysiology ...
Fábio Reis, Rita Pissarra, Henrique Soares, Paulo Soares, Hercília Guimarães   +4 more
doaj   +1 more source

Local Drug-Induced Modulation of gp130 Receptor Signaling Delays Disease Progression in a Pig Model of Temporo-Mandibular Joint Osteoarthritis

Frontiers in Dental Medicine, 2022
Temporomandibular joint disorders (TMJs) are a multifaceted group of chronic disorders characterized by stiffness in the jaw, limited jaw mobility and pain when opening or closing the mouth.
Nancy Q. Liu, Shuo Chen, Shuo Chen, Dawei Geng, Dawei Geng, Jie Lei, Jie Lei, Jiankang Zhang, Jiankang Zhang, Liangliang Li, Liangliang Li, Yucheng Lin, Yucheng Lin, Yuxin Ouyang, Ruzanna Shkhyan, Ben Van Handel, Fangzhou Bian, Tadiwanashe Mkaratigwa, Yang Chai, Yang Chai, Denis Evseenko, Denis Evseenko   +21 more
doaj   +1 more source

Research progress on the regulation of the pathogenesis of melanoma by miRNAs and its related drugs

Pifu-xingbing zhenliaoxue zazhi, 2023
Melanoma is a highly malignant and aggressive cancer originating from melanocytes. Early diagnosis and surgical resection can achieve a good prognosis in some patients.
Hongxia CHEN, Sai CHEN, Xu WANG, Li ZHANG, Jian SHI   +4 more
doaj   +1 more source

Inspection on the Mechanism of SARS-CoV-2 Inhibition by Penciclovir: A Molecular Dynamic Study

Molecules, 2022
In recent years, humanity has had to face a critical pandemic due to SARS-CoV-2. In the rapid search for effective drugs against this RNA-positive virus, the repurposing of already existing nucleotide/nucleoside analogs able to stop RNA replication by ...
Micaela Giannetti, Claudia Mazzuca, Giorgio Ripani, Antonio Palleschi   +3 more
doaj   +1 more source

Investigation of M2 macrophage-related gene affecting patients prognosis and drug sensitivity in non-small cell lung cancer: Evidence from bioinformatic and experiments

Frontiers in Oncology, 2022
BackgroundThe progression process of lung cancer can be accelerated by M2 macrophages. However, genes that affect M2 macrophage polarization remain unidentified.MethodsThe Cancer Genome Atlas, Gene Expression Omnibus, and Arrayexpress databases were used
Zhen Zeng, Jiachen Yu, Zhuo Yang, Kangming Du, Yuewei Chen, Lei Zhou   +5 more
doaj   +1 more source

Barriers and Challenges in Performing Pharmacokinetic Studies to Inform Dosing in the Neonatal Population

Pharmacy, 2020
A number of barriers and challenges must be overcome in order to conduct the pharmacokinetic studies that are urgently needed to inform the selection and dosing of medication in neonates. However, overcoming these barriers can be difficult.
Kate O’Hara, Jennifer H Martin, Jennifer J Schneider   +2 more
doaj   +1 more source

The Role of Intra-Patient Variability of Tacrolimus Drug Concentrations in Solid Organ Transplantation: A Focus on Liver, Heart, Lung and Pancreas

Pharmaceutics, 2022
Tacrolimus, the keystone immunosuppressive drug administered after solid organ transplantation, presents a narrow therapeutic index and wide inter- and intra-patient pharmacokinetic variability (IPV).
Gwendal Coste, Florian Lemaitre
doaj   +1 more source

The G4 Resolvase DHX36 Possesses a Prognosis Significance and Exerts Tumour Suppressing Function Through Multiple Causal Regulations in Non-Small Cell Lung Cancer

Frontiers in Oncology, 2021
Lung cancer is one of the most prevalent cancers in both men and women worldwide. The nucleic acid G4 structures have been implicated in the transcriptional programmes of cancer-related genes in some cancers such as lung cancer.
Yuxin Cui, Zhilei Li, Junxia Cao, Jane Lane, Emily Birkin, Xuefei Dong, Lijian Zhang, Wen G. Jiang   +7 more
doaj   +1 more source