Results 1 to 10 of about 11,912,035 (384)

Engineering exosomes for targeted drug delivery

open access: yesTheranostics, 2021
Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be incorporated into exosomes and then delivered to specific types of cells or ...
Yujie Liang   +3 more
semanticscholar   +1 more source

Controlled Drug Delivery Systems: Current Status and Future Directions

open access: yesMolecules, 2021
The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. Conventional drug delivery systems (tablets, capsules, syrups, ointments, etc.) suffer from poor bioavailability and ...
Shivakalyani Adepu, S. Ramakrishna
semanticscholar   +1 more source

Are There Neural Overlaps of Reactivity to Illegal Drugs, Tobacco, and Alcohol Cues? With Evidence From ALE and CMA

open access: yesFrontiers in Psychiatry, 2022
Abuses of most illegal drugs, including methamphetamine, marijuana, cocaine, heroin, and polydrug, are usually in conjunction with alcohol and tobacco.
HuiLing Li   +9 more
doaj   +1 more source

Advances in covalent drug discovery

open access: yesNature reviews. Drug discovery, 2022
Covalent drugs have been used to treat diseases for more than a century, but tools that facilitate the rational design of covalent drugs have emerged more recently.
L. Boike   +2 more
semanticscholar   +1 more source

Development and Clinical Translation of Approved Gene Therapy Products for Genetic Disorders

open access: yesFrontiers in Genetics, 2019
The field of gene therapy is striving more than ever to define a path to the clinic and the market. Twenty gene therapy products have already been approved and over two thousand human gene therapy clinical trials have been reported worldwide.
Alireza Shahryari   +14 more
doaj   +1 more source

Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation

open access: yesmBio, 2020
New antimalarial drugs are needed. The benzoxaborole AN13762 showed excellent activity against cultured Plasmodium falciparum, against fresh Ugandan P. falciparum isolates, and in murine malaria models.
Kirthana M. V. Sindhe   +9 more
doaj   +1 more source

Cathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug Candidate

open access: yesFrontiers in Neurology, 2015
There currently is no therapeutic drug treatment for traumatic brain injury (TBI) despite decades of experimental clinical trials. This may be because the mechanistic pathways for improving TBI outcomes have yet to be identified and exploited. As such,
Gregory eHook   +5 more
doaj   +1 more source

Drug Interactions in Iranian Veterans With Chronic Spinal Cord Injury - A Descriptive Study

open access: yesInternational Clinical Neuroscience Journal, 2020
Background: Veterans with chronic spinal cord injury usually have various comorbidities. They are, therefore, visited by different doctors and use different medications. It is necessary to monitor the health of these veterans. One of the important issues
Ashkan Divanbeigi   +5 more
doaj   +1 more source

Parents, Peers, and Campus Involvement in the Transition to College

open access: yesJournal of College Orientation, Transition, and Retention, 2010
The purpose of this research was to examine factors that contribute to a successful transition into college. It acknowledges the importance of parents, peers, and campus involvement during this developmental period. Ninety-six college freshmen were given
Jacquelyn M. Norris, Nina S. Mounts
doaj   +1 more source

FUNCTIONAL ANALYSIS OF THE WEBBING USED IN AUTO SEATBELTS [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2016
The reason this paper was made was to identify the functions with the highest importance factor of webbing used in auto seatbelts. For these functions to satisfy all the requirements of operating, functions resulted from analyzing the properties of the ...
DRUG (LUCA) Alexandra, CIOARÄ‚ Ioan
doaj  

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