Definitions, 2020 The Food and Drug Administration is responsible for maintaining a national program to protect the public health from unnecessary and harmful radiation emitted by radiation products.
Arif Subhan
semanticscholar +1 more source
Repression of the stress granule protein G3BP2 inhibits immune checkpoint molecule PD‐L1
Molecular Oncology, EarlyView., 2022 Mounting evidence suggests that cancer stemness and immunosuppression are related, but the underlying mechanisms are not clear. We previously reported that the stress granule‐associated protein G3BP2 is involved in regulating tumor‐initiating (stem) cells.
Yanhong Zhang +3 more
wiley +1 more source
Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance
Molecular Oncology, EarlyView., 2023 Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela +2 more
wiley +1 more source
High-Throughput Screening and Identification of Human Adenovirus Type 5 Inhibitors
Frontiers in Cellular and Infection Microbiology, 2021 Human adenovirus infections can develop into diffuse multi-organ diseases in young children and immunocompromised patients, and severe cases can lead to death. However, there are no approved antiviral drugs available to treat adenovirus diseases. In this
Xiaojing Wen +12 more
doaj +1 more source
The battle for autophagy between host and influenza A virus
Virulence, 2022 Influenza A virus (IAV) is an infectious pathogen, threatening the population and public safety with its epidemics. Therefore, it is essential to better understand influenza virus biology to develop efficient strategies against its pathogenicity ...
Ao Zhou +5 more
doaj +1 more source
Hyperbolic Molecular Representation Learning for Drug Repositioning [PDF]
arXiv, 2022 Learning accurate drug representations is essential for task such as computational drug repositioning. A drug hierarchy is a valuable source that encodes knowledge of relations among drugs in a tree-like structure where drugs that act on the same organs, treat the same disease, or bind to the same biological target are grouped together.
arxiv
AMFPMC -- An improved method of detecting multiple types of drug-drug interactions using only known drug-drug interactions [PDF]
arXiv, 2023 Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is essential, however it is costly and time-consuming.
arxiv
NeuroCADR: Drug Repurposing to Reveal Novel Anti-Epileptic Drug Candidates Through an Integrated Computational Approach [PDF]
arXiv, 2023 Drug repurposing is an emerging approach for drug discovery involving the reassignment of existing drugs for novel purposes. An alternative to the traditional de novo process of drug development, repurposed drugs are faster, cheaper, and less failure prone than drugs developed from traditional methods.
arxiv
ROSTOUCÍ NEBEZPEČÍ OBCHODOVÁNÍ S DROGAMI A JEJICH ZNEUŽÍVÁNÍ V NIGÉRII [PDF]
ACC Journal, 2022 Tento článek zkoumá osoby, trendy, techniky a pohnutky, které jsou zodpovědné za nedávný nárůst zneužívání drog a obchodování s nimi v Nigérii.
Ajiboye Babatope Matthew
doaj +1 more source
Medical Knowledge Graph QA for Drug-Drug Interaction Prediction based on Multi-hop Machine Reading Comprehension [PDF]
, 2022 Drug-drug interaction prediction is a crucial issue in molecular biology. Traditional methods of observing drug-drug interactions through medical experiments require significant resources and labor. This paper presents a medical knowledge graph question answering model, dubbed MedKGQA, that predicts drug-drug interaction by employing machine reading ...
arxiv +1 more source