Advances in covalent drug discovery
Nature reviews. Drug discovery, 2022 Covalent drugs have been used to treat diseases for more than a century, but tools that facilitate the rational design of covalent drugs have emerged more recently.
L. Boike +2 more
semanticscholar +1 more source
Metabolomics to unveil and understand phenotypic diversity between pathogen populations [PDF]
, 2010 Visceral leishmaniasis is caused by a parasite called Leishmania donovani, which every year infects about half a million people and claims several thousand lives. Existing treatments are now becoming less effective due to the emergence of drug resistance.
A Kamleh +63 more
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Market Analysis of Synthetic Drugs: Amphetamine-type Stimulants, New Psychoactive Substances [PDF]
, 2017 An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...
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ANALISIS YURIDIS SOSIOLOGIS PEMBINAAN NARAPIDANA PENYALAHGUNAAN NARKOTIKA UNTUK DIRI SENDIRI DI LEMBAGA PEMASYARAKATAN UMUM (Studi di Lembaga Permasyarakatan Kelas II A Kerobokan Badung Bali) [PDF]
, 2023 The issue of drug abuse in Indonesia is currently very concerning. Drug abuse is a very serious problem. Despite increased law enforcement efforts against drugs, drug trafficking continues to rise due to several factors, including inadequate ...
Riduan, Rizaldi
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Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier.
Polymers, 2011 In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications.
Hirenkumar K. Makadia, S. Siegel
semanticscholar +1 more source
Drug Distribution and Stent Retention of Drug Eluting Stents [PDF]
, 2008 In this paper the examinations of drug eluting coronary stents are shown, such as the morphology of the coatings before expansion, drug distribution, the methodology and the value of stent retention.
Balázs, T. +3 more
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Nucleic Acids Res., 2012 Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers for response to drugs. The Genomics of Drug Sensitivity in Cancer (GDSC) database (www.cancerRxgene.org) is the largest public ...
Wanjuan Yang +16 more
semanticscholar +1 more source
Drug Possession Arrests Reported in Alaska, 1986–2017 — Drug Types by Sex [PDF]
, 2018 Underlying data is available in both Excel and PDF format. (Download below.)This fact sheet presents data on drug possession arrests by type of drug and sex of arrestee as reported by Alaska law enforcement agencies for the 32-year period 1986 to 2017 ...
Ervin, Benjamin
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, 2014 Practically, all chemotherapeutic agents lead to drug resistance. Clinically, it is a challenge to determine whether resistance arises prior to, or as a result of, cancer therapy.
A. Lorz +37 more
core +1 more source
The use of drug calendars for the diagnosis of cutaneous drug eruptions in the age of electronic medical records [PDF]
, 2020 A morbilliform drug eruption is the most common condition leading to a dermatology consultation for a patient in the hospital. Timing is an important diagnostic tool since the onset of a skin rash usually takes place within days-to-weeks of the start of ...
Cohen, Philip R, Grossman, Marc E
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