Results 1 to 10 of about 12,064,988 (403)

Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-Naïve chronic HBV patients [PDF]

, 2013
Background: Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, the development of drug resistance is a major limitation to their long-term effectiveness.
Abedi, F., Alavian, S.M., Ataei, B., Azad, T.M., Daram, M., Fazeli, Z., Ghamari, S., Goodarzi, Z., Jazayeri, S.M., Judaki, M.A., Kalantari, E., Karimzadeh, H., Keyvani, H., Khedive, A., Mahabadi, M., Mahmoodi, M., Malekzadeh, R., Mansour-Ghanaei, F., Montazeri, G., Moradi, A., Nejatizadeh, A., Norouzi, M., Pourhosseingholi, M.A., Rafatpanah, H., Ramezani, F., Saberfar, E., Saberfiroozi, M., Samimirad, K., Sanei-Moghaddam, I., Sarizadeh, G., Sayad, B., Somi, M.H., Yaran, M., Ziee, M.   +33 more
core   +1 more source

Detecting a signal in the noise : Monitoring the global spread of novel psychoactive substances using media and other open source information [PDF]

, 2015
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no ...
Canadian Community Epidemiology Network On Drug Use, Center for Substance Abuse Research, European Monitoring Centre For Drugs And Drug Addiction, Sumnall H   +3 more
core   +1 more source

Nanobiosystems for Antimicrobial Drug-Resistant Infections

Nanomaterials, 2021
The worldwide increased bacterial resistance toward antimicrobial therapeutics has led investigators to search for new therapeutic options. Some of the options currently exploited to treat drug-resistant infections include drug-associated nanosystems ...
Foteini Gkartziou, Nikolaos Giormezis, Iris Spiliopoulou, Sophia G. Antimisiaris   +3 more
doaj   +1 more source

Integrated Analysis Reveals the Potential Significance of HDAC Family Genes in Lung Adenocarcinoma

Frontiers in Genetics, 2022
Histone deacetylases comprise a family of 18 genes, and classical HDACs are a promising class of novel anticancer drug targets. However, to date, no systematic study has been comprehensive to reveal the potential significance of these 18 genes in lung ...
Congkuan Song, Weichen Lin, Heng Meng, Ning Li, Qing Geng   +4 more
doaj   +1 more source

Genetic insight into the putative causal proteins and druggable targets of osteoporosis: a large-scale proteome-wide mendelian randomization study

Frontiers in Genetics, 2023
Background: Osteoporosis is a major causative factor of the global burden of disease and disability, characterized by low bone mineral density (BMD) and high risks of fracture.
Zhichong Wu, Zhichong Wu, Zhichong Wu, Kenneth Guangpu Yang, Kenneth Guangpu Yang, Kenneth Guangpu Yang, Kenneth Guangpu Yang, Kenneth Guangpu Yang, Tsz-Ping Lam, Jack Chun Yiu Cheng, Zezhang Zhu, Zezhang Zhu, Zezhang Zhu, Wayne Yuk-Wai Lee, Wayne Yuk-Wai Lee, Wayne Yuk-Wai Lee, Wayne Yuk-Wai Lee, Wayne Yuk-Wai Lee   +17 more
doaj   +1 more source

Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations [PDF]

, 2014
Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention.
Bown, James L., Goltsov, Alexey, Goltsov, Gregory, Harrison, David J., Langdon, Simon P.   +4 more
core   +3 more sources

Study on drug-induced parkinsonism and its clinical patterns in Eastern Indian population

APIK Journal of Internal Medicine, 2023
Background: Drug-induced parkinsonism (DIP) is important as it is reversible if identified and treated early. We present herewith various clinical patterns and drugs commonly causing DIP.
Praveen Kumar Yadav
doaj   +1 more source

Recent updates on incubation of drug craving: a mini-review [PDF]

, 2015
Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural ...
Abdolahi, Bedi, Bienkowski, Chauvet, Chauvet, Conrad, Counotte, Fanous, Gawin, Grimm, Grimm, Guillem, Halbout, Hollander, Koya, Krasnova, Lee, Li, Li, Li, Loweth, Lu, Lu, Lu, Ma, Marchant, Neisewander, Pickens, Purgianto, Shalev, Shepard, Solinas, Sorge, Theberge, Thiel, Thiel, Tran-Nguyen, Uejima, Wang, Xi   +39 more
core   +1 more source

Influence of pharmaceutical representatives on prescription decisions by physicians in Qassim province

Journal of Family Medicine and Primary Care, 2022
Introduction: Pharmaceutical representatives are an important part of the marketing of pharmaceutical products and an important source of prescribing information for common practitioners.
Waleed M Altowayan, Abdullah Alshubaili
doaj   +1 more source

‘Initiation into drug use’ addendum: findings from the DUMA program [PDF]

, 2012
The age at which an individual first experiments with illicit drugs has been of significant interest to policymakers and practitioners, primarily because research has persistently shown a link between early juvenile onset of drug use and less favourable ...
Jason Payne, Josh Sweeney
core   +1 more source