Results 71 to 80 of about 8,815 (184)

Cerebral in situ ischemic postconditioning: From bench to bedside and beyond

Neuroprotection, EarlyView.
This review explores the translational potential of in situ ischemic postconditioning in acute ischemic stroke. Preclinical and clinical evidence is summarized to highlight its promise as a neuroprotective strategy in the era of endovascular therapy.
Xiao Jiang, Wenbo Zhao, Yongbo Xu, Fanlei Meng, Ming Wei   +4 more
wiley   +1 more source

In vitro determination of drug transfer from drug-coated balloons.

PLoS ONE, 2013
Drug-coated balloons are medical devices designed to locally deliver drug to diseased segments of the vessel wall. For these dosage forms, drug transfer to the vessel wall needs to be examined in detail, since drug released into the blood is cleared from
Anne Seidlitz, Nadine Kotzan, Stefan Nagel, Thomas Reske, Niels Grabow, Claus Harder, Svea Petersen, Katrin Sternberg, Werner Weitschies   +8 more
doaj   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Becoming monstrous: Beauty norms, body image, and discursive limits on compassion in The Substance

Nutrition &Dietetics, EarlyView.
Abstract Aim This study analyses the Hollywood body horror film The Substance to explore how Western beauty culture regulates emotions and bodies. It aims to explore compassion within dominant body image discourses and considers how this impacts dietetic care. Methods Using Foucauldian discourse analysis informed by affect theory, the film was analysed
Phillip Joy
wiley   +1 more source

Analysis of drug gene detection after intracranial drug-coated balloon operation

Guoji laonian yixue zazhi
[Objective] To observe the difference between antiplatelet therapy after drug-coated balloon angioplasty guided by drug gene detection and conventional antiplatelet therapy, and to evaluate the benefit of drug gene guided medication. [Methods] 80 elderly
Wu Mingxin, Qin Peng, Xu Shaowen, Zhang Qizhi   +3 more
doaj   +1 more source

Healing of femoral artery dissection after drug-coated balloon angioplasty: A case report with intravascular ultrasonography and angioscopy images

SAGE Open Medical Case Reports, 2019
Early 80s male with intermitted claudication underwent endovascular therapy for atherosclerotic stenosis at left external iliac artery and middle of superficial femoral artery.
Taketsugu Tsuchiya, Minako Oda, Takaaki Takamura, Katsuhide Kitagawa, Koji Kajinami, Michihiko Kitayama   +5 more
doaj   +1 more source

Pharmacological inhibition of hydroxysteroid 11‐beta dehydrogenase type 1 (11‐βHSD1) after myocardial infarction preserves cardiac function in a translational mini‐pig model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi, Raimondo Ascione, Shazia Khan, Thomas Johnson, Eva Sammut, Vito Domenico Bruno, Daniel Baz Lopez, Carol‐Anne James, Joanna Simpson, Natalie Z. Homer, Michael Millar, Trisha Singh, Alex von Kreigsheim, Nick L. Mills, Brian R. Walker, Ruth Andrew, Scott P. Webster, Andrew Whittaker, Adrian Freeman, Gillian A. Gray   +19 more
wiley   +1 more source

Sirolimus-coated Eustachian tube balloon dilatation for treating Eustachian tube dysfunction in a rat model

Scientific Reports
Eustachian tube balloon dilatation (ETBD) has shown promising results in the treatment of ET dysfunction (ETD); however, recurrent symptoms after ETBD frequently occur in patients with refractory ETD.
Jeon Min Kang, Song Hee Kim, Dae Sung Ryu, Yubeen Park, Dong-Sung Won, Ji Won Kim, Jun-Kyu Park, Hong Ju Park, Jung-Hoon Park   +8 more
doaj   +1 more source

Synaptic ultrastructural alterations in human focal cortical dysplasia: Insights from volume electron microscopy

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a developmental malformation of the cerebral cortex and a leading cause of drug‐resistant epilepsy in children and young adults. Disruption of the excitation–inhibition (E–I) balance is a hallmark of neuronal hyperexcitability in FCD, yet the underlying synaptic ultrastructural changes remain poorly ...
Gyu Hyun Kim, Na‐Young Seo, Seung‐Ki Kim, Jae‐Kyung Won, Yang Hoon Huh, Ji Yeoun Lee, Kea Joo Lee   +6 more
wiley   +1 more source

A pilot study of a novel paclitaxel-coated angioplasty catheter for lower extremity peripheral artery disease: a pilot study

Polish Journal of Thoracic and Cardiovascular Surgery, 2023
Serpil Şahin, Mehmet Ali Yılmaz
doaj   +1 more source