Results 101 to 110 of about 1,915,304 (214)

GMP‐compliant production, validation and dosimetry of clinical grade [18F]3‐(3‐fluoropropyl)‐2‐phenyl‐2,3‐dihydrobenzo[d]thiazole ([18F]FPBT) for oxidative stress PET imaging

British Journal of Pharmacology, Volume 183, Issue 20, Page 6028-6045, October 2026.
Background and Purpose Oxidative stress plays a critical role in the pathophysiology of various diseases, yet current methods for its non‐invasive detection remain limited. This study aimed to systematically validate a superoxide‐selective PET tracer, [18F]FPBT, for the early diagnosis and therapeutic monitoring of oxidative stress‐related conditions ...
Hua Zhang, Fangfang Sun, Chun Li, Xin Wang, Yuexuan Song, Lu Jiang, Paul Gape, Samantha Y. A. Terry, Shujun He, Ran Yan, Zhi Lu   +10 more
wiley   +1 more source

N8‐Modified Quino[4,3,2‐Kl]acridines as Promising Antimalarial G‐Quadruplex Ligands

ChemBioChem, Volume 27, Issue 17, 14 September 2026.
A series of extended aromatic compounds with tunable substituents was synthesized using a multistep methodology which allows various substitutions of the 8H‐quino[4,3,2‐kl]acridine scaffold. This chemical series appeared as a promising way to new antimalarial drug candidates with high activity (IC50 < 100 nM), exhibiting a novel mechanism of action ...
Steve Saulnier, Marco Antônio G. B. Gomes, Mariam Salim, Maxime Guichonnet, Michel Nguyen, Laure Vendier, Flore Nardella, Jean‐Michel Augereau, Dennis Gomez, Anne Robert, Françoise Benoit‐Vical   +10 more
wiley   +1 more source

Drug-eluting balloon versus bare-mental stent and drug-eluting stent for de novo coronary artery disease: A systematic review and meta-analysis of 14 randomized controlled trials

PLoS ONE, 2017
Background Drug-eluting balloon (DEB) has become an alternative option to drug-eluting stent (DES) for the treatment of in-stent restenosis (ISR). However, the effect of drug-eluting balloon with regular bare-mental stent (BMS) in de novo coronary artery
K. Cui, S. Lyu, Xiantao Song, F. Yuan, Feng Xu, Min Zhang, Wei Wang, Dong-Feng Zhang, Jing Dai   +8 more
semanticscholar   +1 more source

Efficacy of drug-eluting balloon in patients with bare-metal or drug-eluting stent restenosis. [PDF]

, 2014
INTRODUCTION: In spite of improving results, the treatment of in-stent restenosis (ISR) of bare-metal stents (BMS), and particularly drug-eluting stents (DES), is a challenging clinical problem.
Bárczi, György, Becker, Dávid, Ruzsa, Zoltán, Merkely, Béla Péter, Kohar, K., Molnár, Levente Domonkos, Jambrik, Zoltán, Berta, Balázs, Szabó, G., Gellér, László Alajos   +9 more
core   +1 more source

Drug-coated balloon angioplasty versus drug-eluting stent implantation in patients With coronary stent restenosis

, 2021
Background: In patients with coronary in-stent restenosis (ISR) requiring reintervention, it is unclear if the choice of treatment should depend on whether the restenotic stent was a bare-metal stent (BMS) or a drug-eluting stent (DES).Objectives: This ...
Leos Pleva (10865607), Fernando Alfonso (848316), Duk-Woo Park (796012), José P S Henriques (10865656), Adnan Kastrati (95640), Runlin Gao (715312), Jan Baan (4586296), Bo Xu (233514), Bimmer E P M Claessen (10865580), Ralf Degenhardt (10865599), Pilar Jiménez-Quevedo (5638394), Seung-Jung Park (95648), Pavel Kukla (10865626), Martin Unverdorben (10865644), Christoph K Naber (10865652), Tom Adriaenssens (397863), Daniele Giacoppo (10865563), María J Pérez-Vizcayno (10865592), Javier Cuesta (2653306), Christoph Jensen (2806795), Robert Byrne (8134437), Do-Yoon Kang (5958893)   +21 more
core   +1 more source

Drug-Coated Balloon Angioplasty Versus Drug-Eluting Stent Implantation in Patients With Coronary Stent Restenosis

, 2020
Background: In patients with coronary in-stent restenosis (ISR) requiring reintervention, it is unclear if the choice of treatment should depend on whether the restenotic stent was a bare-metal stent (BMS) or a drug-eluting stent (DES).
Duk-Woo Park (796012), José P S Henriques (10865656), Unverdorben, Martin, Adriaenssens, Tom, Henriques, José P. S., Kastrati, Adnan, Ralf Degenhardt (10865599), Pilar Jiménez-Quevedo (5638394), Seung-Jung Park (95648), Jiménez-Quevedo, Pilar, Martin Unverdorben (10865644), Xu, Bo, Tom Adriaenssens (397863), Giacoppo, Daniele, Pleva, Leos, Baan, Jan, Kukla, Pavel, Gao, Runlin, Kang, Do-Yoon, Daniele Giacoppo (10865563), Christoph Jensen (2806795), Pérez-Vizcayno, María J., Claessen, Bimmer E. P. M., Cuesta, Javier, Leos Pleva (10865607), Fernando Alfonso (848316), Alfonso, Fernando, Adnan Kastrati (95640), Runlin Gao (715312), Jan Baan (4586296), Bo Xu (233514), Naber, Christoph K., Bimmer E P M Claessen (10865580), Pavel Kukla (10865626), Christoph K Naber (10865652), Park, Seung-Jung, María J Pérez-Vizcayno (10865592), Degenhardt, Ralf, Jensen, Christoph, Javier Cuesta (2653306), Park, Duk-Woo, Robert Byrne (8134437), Byrne, Robert A., Do-Yoon Kang (5958893)   +43 more
core   +1 more source

Drug-eluting balloon versus standard balloon angioplasty for infrapopliteal arterial revascularization in critical limb ischemia: 12-month results from the IN.PACT DEEP randomized trial. [PDF]

, 2014
BACKGROUND Drug-eluting balloons (DEB) may reduce infrapopliteal restenosis and reintervention rates versus percutaneous transluminal angioplasty (PTA) and improve wound healing/limb preservation.
Kent, K. Craig, Baumgartner, Iris, Bosiers, Marc, Peeters, Patrick, Kent, K Craig, Snead, David B., Rocha-Singh, Krishna J, Rocha-Singh, Krishna J., Micari, Antonio, Landini, Mario, Scheinert, Dierk Wolfgang, Vermassen, Frank, Zeller, Thomas, Scheinert, Dierk, Brodmann, Marianne, Snead, David B   +15 more
core   +2 more sources

BAlloon versus Stenting in severe Ischaemia of the Leg-3 (BASIL-3): study protocol for a randomised controlled trial

Trials, 2017
Background Severe limb ischaemia (SLI) is defined as the presence of rest pain and/or tissue loss secondary to lower extremity atherosclerotic peripheral arterial disease.
Benjamin D. Hunt, Matthew A. Popplewell, Huw Davies, Lewis Meecham, Hugh Jarrett, Gareth Bate, Margaret Grant, Smitaa Patel, Catherine Hewitt, Lazaros Andronis, Jonathan J. Deeks, Andrew Bradbury, on behalf of the BASIL-3 Collaborative Group   +12 more
doaj   +1 more source

Evaluation of pressure sensitive adhesives for drug eluting balloon

, 2011
Atheroscelerosis is a cardiovascular disease caused by accumulation of plaque in the walls of the blood vessel. There are many current medical devices which are used to treat atheroscelerosis.
Wang, Dione Qian Ying
core  

3D-printed, citrate-based bioresorbable vascular scaffolds for coronary artery angioplasty

Bioactive Materials
Fully bioresorbable vascular scaffolds (BVSs) aim to overcome the limitations of metallic drug-eluting stents (DESs). However, polymer-based BVSs, such as Abbott's Absorb, the only US FDA-approved BVS, have had limited use due to increased strut ...
Yonghui Ding, Liam Warlick, Mian Chen, Eden Taddese, Caralyn Collins, Rao Fu, Chongwen Duan, Xinlong Wang, Henry Ware, Cheng Sun, Guillermo Ameer   +10 more
doaj   +1 more source