Results 51 to 60 of about 21,695 (218)
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
Advanced Science, EarlyView.In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Perfil dos pacientes submetidos à angioplastia trasluminal coronariana com stents farmacológicos no Instituto de Cardiologia de Santa Catarina. [PDF]
, 2007 Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Aquino, Vivian Wuerges de
core
Bioabsorbable Endovascular Adhesive Tape (BEAT) for Improving Vascular Regeneration
Advanced Science, EarlyView.A bioabsorbable endovascular adhesive tape (BEAT) platform based on a hierarchical polyelectrolyte complex is developed to enhance drug delivery in the DCB system. The coating enables rapid transfer to the vessel, provides short‐term mechanical support, and promotes both immediate transfer and long‐term retention of drugs at the lesion site.
Jiarong Wang +13 more
wiley +1 more source
Drug-eluting balloon: Stents bald überflüssig?
, 2010 Seit Gruntzig 1974 die erste Femoralarterie mittels perkutaner transluminaler Angioplastie (PTA) behandelt hat, ist die Methode dank enormer technischer Entwicklungen nicht mehr aus der modernen Behandlung koronarer und peripherer Arterien wegzudenken.
Stricker, H, Amann-Vesti, B R
openaire +1 more source
Advanced Science, EarlyView.This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He +17 more
wiley +1 more source
Drug-Eluting Balloon: An Overview of Clinical Evidences on Safety and Effectiveness
Journal of Pharmacoeconomics and Pharmaceutical Management, 2015 Background: Recent advances in the intravascular diseases have led to the entrance of drug-eluting balloon (DEB) technology. The DEB is a relatively new and easier way to treat vascular stenosis.
Khosro Keshavarz +4 more
doaj
Efficacy and risks of drug-coated balloon treatment for coronary artery disease: A meta-analysis
Heliyon, 2023 Introduction: Coronary artery disease (CAD) often leads to myocardial ischemia and impaired cardiac function, significantly impacting the well-being and quality of life (QOL) of individuals.
Xinghua Bai +4 more
doaj +1 more source
Current Status of Drug-Eluting Stents and Drug-Eluting Balloons for the Superficial Femoral Artery [PDF]
Current Surgery Reports, 2013 The endovascular management of symptomatic atherosclerotic superficial femoral artery disease is challenging and requires consideration of unique anatomic, hemodynamic, and biomechanical factors. For innovative local drug delivery technologies to have a cost-effective and clinically meaningful benefit, they must provide patency rates in more complex ...
Joy P, Walker, Christopher D, Owens
openaire +2 more sources
BMEMat, EarlyView.A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen +9 more
wiley +1 more source
Pakistan Journal of Medicine and DentistryDrug-eluting balloons (DEBs) are increasingly used in percutaneous coronary intervention (PCI), particularly for patients with small vessel disease or those unsuitable for stent implantation.
Muhammad Iqbal +3 more
doaj +1 more source