Results 81 to 90 of about 51,654 (292)

Trends and Outcomes Following Percutaneous Coronary Intervention in Patients With Myeloproliferative Neoplasms: Insights From National Database

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Myeloproliferative neoplasms (MPN) are associated with an increased cardiovascular risk including acute coronary syndrome. However, there is a lack of comprehensive data regarding the rate of percutaneous coronary intervention (PCI), as well as the in‐hospital characteristics and outcomes for MPN patients.
Song Peng Ang, Jia Ee Chia, Chayakrit Krittanawong, Robert N. Piana, Kwan Lee, Chadi Ayoub, JR Exequiel Pineda, David Song, Debabrata Mukherjee   +8 more
wiley   +1 more source

Second Generation Drug-Eluting Stents: A Review of the Everolimus-Eluting Platform

Clinical Medicine Insights: Cardiology, 2013
Everolimus-eluting stents (EES) represent the next generation of drug-eluting stents (DES). Important design modifications include thin strut stent backbones, less inflammatory and more biocompatible polymers, and lower drug dosing.
Matthew G. Whitbeck, Robert J. Applegate
doaj   +1 more source

Long-Term Efficacy and Safety of Paclitaxel-Eluting Balloon for the Treatment of Drug-Eluting Stent Restenosis 3-Year Results of a Randomized Controlled Trial [PDF]

ObjectivesThis study sought to investigate the long-term comparative efficacy and safety of paclitaxel-eluting balloon (PEB), paclitaxel-eluting stent (PES), or balloon angioplasty (BA) for the treatment of drug-eluting stent restenosis.BackgroundThe ...
Byrne, Robert A., Cassese, Salvatore, Fusaro, Massimiliano, Hoppmann, Petra, Kastrati, Adnan, Kufner, Sebastian, Laugwitz, Karl-Ludwig, Neumann, Franz-Josef, Schulz-Schüpke, Stefanie, Schunkert, Heribert, Valeskini, Marco   +10 more
core   +1 more source

On the role of specific drug binding in modelling arterial eluting stents [PDF]

, 2016
In this paper we consider drug binding in the arterial wall following delivery by a drug-eluting stent. Whilst it is now generally accepted that a non-linear saturable reversible binding model is required to properly describe the binding process, the ...
AR Tzafriri, AR Tzafriri, CM Groh, DA Lauffenburger, F Bozsak, F Bozsak, G Frenning, G Pontrelli, GD Dangas, Giuseppe Pontrelli, RI Hickson, S McGinty, Sean McGinty, TTN Vo   +13 more
core   +1 more source

Impact of Coronary Calcification on Complete Revascularization in Patients With Acute Coronary Syndrome and Multivessel Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary calcification is a well‐known marker of atherosclerotic plaque burden and a determinant of stent under expansion with unfavorable long‐term outcomes. Aims This sub study of the randomized BIOVASC trial aimed to compare immediate complete revascularization (ICR) and staged complete revascularization (SCR) in patients with ...
William Camilleri, Hala Kakar, Jacob J. Elscot, Eric Boersma, Nicolas M. Van Mieghem, Roberto Diletti, Joost Daemen, Elena Ntantou, Jeroen Wilschut, Rutger Jan Nuis, Wijnand K. Den Dekker   +10 more
wiley   +1 more source

A multiphysics modeling approach for in-stent restenosis: Theoretical aspects and finite element implementation [PDF]

arXiv, 2022
Development of in silico models are intrinsic in understanding disease progression in soft biological tissues. Within this work, we propose a fully-coupled Lagrangian finite element framework which replicates the process of in-stent restenosis observed post stent implantation in a coronary artery.
arxiv  

Plaque heterogeneity influences in-stent restenosis following drug-eluting stent implantation: Insights from patient-specific multiscale modelling [PDF]

In-stent restenosis represents a major cause of failure of percutaneous coronary intervention with drug-eluting stent implantation. Computational multiscale models have recently emerged as powerful tools for investigating the mechanobiological mechanisms
Akyildiz A. C., Chiastra C., Corti A., Dal Ferro L., McGinty S., Migliavacca F.   +5 more
core   +1 more source

Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation [PDF]

, 2015
Background: Drug-eluting stents reduce the incidence of in-stent restenosis, but they result in delayed arterial healing and are associated with a chronic inflammatory response and hypersensitivity reactions. Identifying novel interventions to enhance
Baker, Andrew H., Channon, Keith M., Dakin, Rachel S., Diver, Louise A., Douglas, Gillian, Halliday, Crawford A., Kennedy, Simon, McBride, Martin W., McClure, John D., McDonald, Robert A., Miller, Ashley M., Montgomery, Jennifer, Oldroyd, Keith, Robertson, Keith E.   +13 more
core   +1 more source

Enhanced Drug Effect With Cutting Balloon Followed by Drug Coated Balloon in a Rabbit Model

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Drug‐coated balloon (DCB) are effective treatment options for patients with coronary artery disease and using of scoring or cutting balloon before the DCB usage were recommended. However, the effectiveness of lesion preparation with cutting balloons (CB) followed by DCB (CB + DCB) has not been evaluated before.
Manabu Shiozaki, Sho Torii, Yu Sato, Kazuki Aihara, Yuki Matsumoto, Norihito Nakamura, Daiki Suzuki, Ayako Yoshikawa, Yuji Ikari, Gaku Nakazawa   +9 more
wiley   +1 more source

In-silico Analysis of Hemodynamic Indicators in Idealized Stented Coronary Arteries for Varying Stent Indentation [PDF]

In this work, we investigate the effects of stent indentation on hemodynamic indicators in stented coronary arteries. Our aim is to assess in-silico risk factors for in-stent restenosis (ISR) and thrombosis after stent implantation. The proposed model is applied to an idealized artery with Xience V stent for four indentation percentages and three mesh ...
arxiv   +1 more source