Results 51 to 60 of about 39,848 (225)

Application of underdamped Langevin dynamics simulations for the study of diffusion from a drug-eluting stent

open access: yes, 2018
We use a one-dimensional two layer model with a semi-permeable membrane to study the diffusion of a therapeutic drug delivered from a drug-eluting stent (DES).
Farago, Oded, Regev, Shaked
core   +1 more source

Pharmacokinetic analysis after implantation of everolimus-eluting self-expanding stents in the peripheral vasculature [PDF]

open access: yes, 2012
Background: A novel self-expanding drug-eluting stent was designed to release everolimus 225 mu g/cm(2) to prevent restenosis following peripheral arterial intervention.
Hausegger, Klaus A   +7 more
core   +2 more sources

Excessive Ostial Stent Protrusion: Evaluation of Management Strategies and Clinical Outcomes of the Side Flap Technique

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Backgrounds Accurate stent positioning in aorto‐ostial lesions remains challenging due to complex three‐dimensional anatomy, lack of optimal fluoroscopic projections, and high rates of geographic miss. Stent overhang impairs guide catheter re‐engagement and complicates future revascularization.
Gregor Leibundgut   +7 more
wiley   +1 more source

Drug-eluting stents : Insights into safety and indications

open access: yesAnnals of Saudi Medicine, 2008
Currently, more than 4 million patients receive drug-eluting stents worldwide. Despite recent studies and editorials that have stirred controversy and generated tremendous publicity in the lay press related to the safety of drug-eluting stents for the ...
Hassan Walid
doaj  

Outcomes of coronary artery bypass grafting versus percutaneous coronary intervention with second-generation drug-eluting stents for patients with multivessel and unprotected left main coronary artery disease

open access: yesSAGE Open Medicine, 2017
Objectives: To compare the efficacy and safety of percutaneous coronary intervention using second-generation drug-eluting stents with those of coronary artery bypass grafting among patients with multivessel disease and/or unprotected left main coronary ...
Kyriacos Papadopoulos   +2 more
doaj   +1 more source

A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery [PDF]

open access: yes, 2016
Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer.
Jones, Robert L.   +4 more
core   +2 more sources

Successful Management of a Complex Coronary Bifurcation Lesion in Acute Coronary Syndrome Using a Free‐Metal Approach

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT We present the case of a 56‐year‐old male with non‐ST elevation myocardial infarction (NSTEMI) and a complex thrombotic lesion at the ostial left circumflex artery (LCX), extending into bifurcating marginal branches. Due to the high risk of side branch occlusion, a stentless strategy using thrombus aspiration, the reverse wire technique, and ...
Flavius‐Alexandru Gherasie   +1 more
wiley   +1 more source

Advances in Drug Delivery via Biodegradable Ureteral Stent for the Treatment of Upper Tract Urothelial Carcinoma

open access: yesFrontiers in Pharmacology, 2020
Drug eluting ureteral stent is an effective means for local drug delivery to the urinary tract. It can potentially solve a variety of upper urinary tract problems, such as stent-related urinary tract infections and discomfort, ureteral stricture, and ...
Hongli Shan   +6 more
doaj   +1 more source

Variability in ACT Response to Standard UFH Bolus During PCI: A Prospective Study on Determinants of Subtherapeutic Anticoagulation

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Unfractionated heparin (UFH) remains the standard anticoagulant during percutaneous coronary intervention (PCI), with guidelines recommending a target activated clotting time (ACT) of ≥250 s. However, despite receiving a standardized bolus dose, many patients fail to achieve this target.
Manh Cuong Vu   +9 more
wiley   +1 more source

Thrombosis prevention in percutaneous coronary interventions

open access: yesКардиоваскулярная терапия и профилактика, 2009
The introduction of drug-eluting stents has been a major achievement of interventional cardiology. These stents  demonstrate good clinical effectiveness and safety profile.
V. P. Lupanov, A. N. Samko
doaj  

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