Results 281 to 290 of about 2,984,799 (310)

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Gastrointestinal toxicity of antibody-drug conjugates: a pharmacovigilance study using the FAERS database. [PDF]

BMC Pharmacol Toxicol
Shi Y, Yao K, Zhao J, Yue Y, Wu H.
europepmc   +1 more source

Mesoporous Gold Nanospheres Confined Platinum Nanoclusters as Robust ROS and Oxygen Nanogenerators for NIR‐II Hyperthermia Cancer Therapy

Advanced Science, EarlyView.
Mesoporous gold nanospheres confined platinum nanoclusters (MGNSs@Pt) is developed as robust hydroxyl radical and oxygen nanogenerators for multimodal therapies. Their NIR‐II LSPR property also allowed MGSNs to be ideal phototheranostic agents. The chemodynamic and photothermal therapy efficiently induced the tumor cell apoptosis, enabling the MGNSs@Pt
Fei Cun, Jie Chen, Hanxue Li, Yufang Kou, Meiyan Wang, Xiaomin Li, Hui Chen, Jilie Kong   +7 more
wiley   +1 more source

Signal detection and safety analysis of three tyrosine kinase inhibitors for HER-2 positive breast cancer: a retrospective study based on the FAERS database. [PDF]

Front Pharmacol
Tang X, Wang C, Li Y, Tang J, Zhang G, Chen L.   +5 more
europepmc   +1 more source

Living Biotherapeutics Using Nanoparticles‐Armed Cyanobacteria for Boosting Photodynamic‐Immunotherapy of Cancer

Advanced Science, EarlyView.
A schematic illustration of the cyanobacteria‐based biohybrid platform for photodynamic cancer therapy enhanced PDT. The platform continuously outputs O2 (to alleviate tumor hypoxia) and 1O2 (for tumor treatment), achieving improved photodynamic immunotherapy. Abstract The interdisciplinary development of synthetic biology and material sciences propels
Zhengwei Xu, Mingsong Zang, Hui Li, Ruizhen Tian, Zherui Zhang, Wang Liu, Fei Xiao, Xuesha Yan, Yan Zhu, Canhong Zhu, Jiayun Xu, Shuangjiang Yu, Tingting Wang, Hongcheng Sun, Junqiu Liu   +14 more
wiley   +1 more source

Safety considerations and risk mitigation strategies for ketamine use: a comprehensive review. [PDF]

Ann Med Surg (Lond)
Sayad R, Elsaeidy AS, Anis AM, Atef M, Hawash EA, Saad HA, Hamad KAA, Kohaf NA.   +7 more
europepmc   +1 more source

Retrospective analysis of pembrolizumab-related adverse reactions and death outcomes based on the FAERS database. [PDF]

BMC Cancer
Xu H, Huang Y, Zhao N, Hu H, Cao D.
europepmc   +1 more source

Recent Advances in the Management of Dyslipidemia: A Systematic Review. [PDF]

Cureus
Huang JXF, Yousaf A, Moon J, Ahmed R, Uppal K, Pemminati S.   +5 more
europepmc   +1 more source

The characteristics of adverse reactions of three anti-prostate cancer drugs based on Vigiaccess database and bibliometric analysis. [PDF]

Front Pharmacol
Wang J, You J, Huang W, Yuan C, Chen J, Wang F, Wang W, Zhang L.   +7 more
europepmc   +1 more source

Osilodrostat Safety Profile: Findings from Real-World Data in the FAERS Database. [PDF]

J Clin Med
Popa Ilie IR, Butuca A, Homorodean C, Dobrea CM, Morgovan C, Frum A, Ghibu S.   +6 more
europepmc   +1 more source