Results 171 to 180 of about 1,289,803 (292)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Ubiquitination and deubiquitination as critical modulators of NSCLC tumorigenesis and drug resistance. [PDF]

Discov Oncol
Ramalingam PS, Afzal M, Rekha MM, Sahoo S, Pandey SN, Maji C, Goyal K, Ali H, Singh SK, Gupta G, Hussain MS, Balakrishnan P, Arumugam S.   +12 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Artificial intelligence for screening drug resistance in tuberculosis. [PDF]

Indian J Med Res
Mohanvel SK, Radhakrishnan R, Balraj P, Singh N, Danisetty S, Vats H, Chaudhury A, Choudhary H, Rajendran P, Jayaprakasam M, Devi Vadivel S, Preysingh B, Thariyasha S, Anjaiyan S, Chittiboyina S, Dhawan S, Lichade S, Kumari R, Ratnam R, Chandrakar S, Nasir Khan M, Srivastava AK, Roy I, Kingsberry R, Sridharan A, Ramachandran R, Kumar N, Singh M, Rao R, Singh UB, Padmapriyadarsini C, Shanmugam SK.   +31 more
europepmc   +1 more source

Peer Review #2 of "A rapid and accurate method for the detection of four aminoglycoside modifying enzyme drug resistance gene in clinical strains of Escherichia coli by a multiplex polymerase chain reaction (v0.2)"

, 2020

openalex   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

From mechanism to clinic: a panoramic perspective on targeting HMOX1 to overcome drug resistance. [PDF]

J Cancer Res Clin Oncol
Huang D, Ma Y, Gao W, Xie Q.
europepmc   +1 more source

Table S3 from Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations

, 2023
Paul Yenerall, Rahul K. Kollipara, Kimberley Avila, Michael Peyton, Christopher A. Eide, Daniel Bottomly, Shannon K. McWeeney, Yan Liu, Kenneth D. Westover, Brian Druker, John D. Minna, Ralf Kittler   +11 more
openalex   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Clinical application and drug resistance mechanism of gemcitabine. [PDF]

Front Cell Dev Biol
Zhang X, Qi B, Chen J.
europepmc   +1 more source