Results 191 to 200 of about 3,635,615 (259)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Plumbagin Induces Cell Cycle Arrest and Autophagy and Suppresses Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR-Mediated Pathway in Human Pancreatic Cancer Cells [Retraction]. [PDF]

Drug Des Devel Ther
europepmc   +1 more source

Centering the voices of young people who use opioids and youth harm reduction practitioners: insights from an international Youth RISE cohort. [PDF]

Harm Reduct J
Juristia A, Azvian V, Arredondo C, Calzada R, Rivera AC, Wambui S, Etepesit WO, Goodyear T.   +7 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Leveraging Administrative Health Data to Capture Rare Adverse Drug Reactions: Identifying Pediatric Patients With Trimethoprim-Sulfamethoxazole Acute Respiratory Distress Syndrome. [PDF]

Pharmacol Res Perspect
Feldman K, Miller JO, Doane K, Loftis L, Antoon JW, Downes KJ, Goldman JL.   +6 more
europepmc   +1 more source

Notes from the Field: Drug Overdose Deaths in Hotels and Motels - United States, 2022-2024. [PDF]

MMWR Morb Mortal Wkly Rep
Stewart A, Dinwiddie A, Wisdom A, Gilson T.   +3 more
europepmc   +1 more source

Formulation of 5-fluorouracil loaded chitosan-based nanoparticles and evaluation of its cytotoxic effects against MCF-7 human breast cancer cells. [PDF]

PLoS One
Ekpo IA, Ovenseri AC, Abdullateef A, Durmaz B.   +3 more
europepmc   +1 more source

Intranasal Mucosal Atomiser Devices: A Novel Harm Reduction Intervention. [PDF]

Drug Alcohol Rev
Green H, Naren T, Chapman B, Lloyd-Jones M, Crawford S, Membrey D.   +5 more
europepmc   +1 more source

Impact of CFTR modulator concentrations on clinical response in cystic fibrosis. [PDF]

Eur Respir J
Chalamalla AR, Baker E, Ryan KJ, Dowell A, Natt JR, Zemanick ET, Konstan MW, Mayer-Hamblett N, Acosta EP, Guimbellot JS, CHEC-SC investigators.   +10 more
europepmc   +1 more source

Covalent grafting of hyaluronic acid on drug nanocrystals for mucosal delivery.

J Mater Chem B
Fuster MG, Fandiño OE, Ramesh A, Coulter JA, Paredes AJ.   +4 more
europepmc   +1 more source