Results 341 to 350 of about 12,292,416 (404)

Drug–drug interaction with statins

Expert Review of Clinical Pharmacology, 2008
3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors (the so-called statins: atorvastatin, fluvastatin, pravastatin, lovastatin, rosuvastatin and simvastatin) are a well-established class of drugs in the treatment of hypercholesterolemia. Statin monotherapy is generally well tolerated, with a low frequency of adverse events.
A. Corsini, S. Bellosta
openaire   +3 more sources

Drug Repurposing Based on Drug–Drug Interaction

Chemical Biology & Drug Design, 2014
Given the high risk and lengthy procedure of traditional drug development, drug repurposing is gaining more and more attention. Although many types of drug information have been used to repurpose drugs, drug–drug interaction data, which imply possible physiological effects or targets of drugs, remain unexploited.
Ping Wu, Bin Zhou, De-Xin Kong, Rong Wang   +3 more
openaire   +3 more sources

A drug-to-drug interaction package

Computer Methods and Programs in Biomedicine, 1989
This paper describes an electronic database for handling the interactions between active principles administered to various patients. The computer used is a personal computer with adequate mass memory, software, and data obtained from pharmacological sources.
PINCIROLI, FRANCESCO, POZZI, GIUSEPPE
openaire   +4 more sources

Drug-Drug Interactions of Antimalarial Drugs

2018
Malaria is the most important parasitic disease of humans accounting for high morbidity and mortality rates in the tropical and subtropical countries of Africa, Asia, and the Americas. Combination chemotherapy is recommended for treatment of acute uncomplicated malaria as a result of widespread drug resistance.
Tunde Balogun, Gene D. Morse, Fatai A. Fehintola, Waheed A. Adedeji   +3 more
openaire   +2 more sources

Iron as a Drug and Drug–Drug Interactions

2009
• Bioavailabiltiy of oral iron may be enhanced in the presence of reducing agents such as ascorbic acid.
Teresa V. Lewis, Tracy M. Hagemann
openaire   +2 more sources

Drug–drug interactions involving new antiretroviral drugs and drug classes

Current Opinion in Infectious Diseases, 2009
The aim of this article is to review the available data on new antiretroviral agents and the drug-drug interactions studied so far.Several new drugs have been recently approved or are under development for the treatment of HIV infection. The pharmacokinetics of these agents is being studied to provide information about safety and efficacy, and ...
Marta Sousa, Jesse Soodalter, Marta Boffito   +2 more
openaire   +3 more sources

Drug safety, drug quality, drug analysis

Journal of Pharmaceutical and Biomedical Analysis, 2008
Controlling and minimizing the side effects of drugs are the key issues in assuring the safety of drug therapy. Since side effects are inherent properties of the drug material, these cannot be influenced by drug analysts. At the same time drug analysts play a predominant role in assuring the quality of bulk drug materials and drug formulations and this
openaire   +2 more sources

Antibody–drug conjugates come of age in oncology

Nature reviews. Drug discovery, 2023
C. Dumontet, J. Reichert, P. Senter, J. Lambert, A. Beck   +4 more
semanticscholar   +1 more source

World Drug Report 2023

World Drug Report, 2023

semanticscholar   +1 more source

Drug repurposing: progress, challenges and recommendations

Nature reviews. Drug discovery, 2018
S. Pushpakom, Francesco Iorio, P. Eyers, K. J. Escott, Shirley Hopper, A. Wells, A. Doig, Tim Guilliams, Joanna Latimer, Christina McNamee, A. Norris, P. Sanseau, D. Cavalla, M. Pirmohamed   +13 more
semanticscholar   +1 more source