Results 371 to 380 of about 5,685,542 (420)
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1971
The buccal cavity is lined with a mucous membrane which, like the lining of the entire alimentary canal, behaves as a lipoidal barrier to the passage of drugs (Schanker, 1962). In general, drugs penetrate the mucous membrane by simple diffusion and are carried in the blood that richly supplies the salivary glands and their ducts into the general ...
R D Hossie, A. H. Beckett
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The buccal cavity is lined with a mucous membrane which, like the lining of the entire alimentary canal, behaves as a lipoidal barrier to the passage of drugs (Schanker, 1962). In general, drugs penetrate the mucous membrane by simple diffusion and are carried in the blood that richly supplies the salivary glands and their ducts into the general ...
R D Hossie, A. H. Beckett
openaire +2 more sources
Influence of excipients on drug absorption via modulation of intestinal transporters activity
, 2015One of the major factors affecting oral drug bioavailability is the activity of intestinal transport proteins, particularly for the drugs that undergo absorption by active transport mechanism.
P. Thakkar
semanticscholar +1 more source
Interplay of Drug-Metabolizing Enzymes and Transporters in Drug Absorption and Disposition.
Current drug metabolism, 2014In recent years, the functional interplay between drug-metabolizing enzymes (DMEs) and drug transporters (DTs) in drug absorption and disposition, as well as the complex drug interactions (DIs), has become an intriguing contention, which has also been ...
S. Shi, Yunqiao Li
semanticscholar +1 more source
Experimental models for predicting drug absorption and metabolism
Expert Opinion on Drug Metabolism & Toxicology, 2013Introduction: For orally administered drugs, their intestinal absorption and hepatic metabolism are key players for determining a drug's systemic bioavailability and thus therapeutic effect.
S. Alqahtani +2 more
semanticscholar +1 more source
Drug absorption, distribution, metabolism and excretion considerations in critically ill adults
Expert Opinion on Drug Metabolism & Toxicology, 2013Introduction: All critically ill patients require medication to treat organ dysfunction. However, the pharmacokinetics of drugs used to treat these patients is complex due to frequent alterations in drug absorption, distribution, metabolism, and ...
D. Roberts, R. Hall
semanticscholar +1 more source
Journal of the American Medical Association, 1954
To the Editor:— Ergotamine tartrate and caffeine can be absorbed from mucous membrane. Because many patients with migraine or tension headaches are too nauseated to tolerate these drugs by mouth, and because it is difficult to arrange for administration of ergotamine tartrate hypodermically at the onset of an attack, it has been advised that they be ...
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To the Editor:— Ergotamine tartrate and caffeine can be absorbed from mucous membrane. Because many patients with migraine or tension headaches are too nauseated to tolerate these drugs by mouth, and because it is difficult to arrange for administration of ergotamine tartrate hypodermically at the onset of an attack, it has been advised that they be ...
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2009
Oral input is the most convenient route for drug administration so the large majority of drug products are oral dosage forms. This dictates consideration of the timing of drug administration with respect to the time of meal ingestion. There are several reasons for taking a drug with a meal or nutrient beverage. It may be expedient for clinical staff in
Burgunda V. Sweet +3 more
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Oral input is the most convenient route for drug administration so the large majority of drug products are oral dosage forms. This dictates consideration of the timing of drug administration with respect to the time of meal ingestion. There are several reasons for taking a drug with a meal or nutrient beverage. It may be expedient for clinical staff in
Burgunda V. Sweet +3 more
openaire +2 more sources
Drug Absorption and Bioavailability
Medical Journal of Australia, 1978Michael Kennedy, Garry G. Graham
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Dimensional Design and Core–Shell Engineering of Nanomaterials for Electromagnetic Wave Absorption
Advanced Materials, 2022Chunyang Xu, Renchao Che, Renchao Che
exaly