Results 131 to 140 of about 2,691,356 (356)
Formal modelling and design of mobile prescription applications [PDF]
, 2008 Adverse drug effects are a major cause of death in the world with tens of thousand deaths occurring each year because of medication or prescription errors.
Omoregbe, N. A.
core
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Mass administrations of antimalarial drugs.
, 2003 Administration of antimalarial drugs to whole populations has been used as a malaria-control measure for more than 70 years. Drugs have been administered either directly as a full therapeutic course of treatment or indirectly through the fortification of
Greenwood, Brian M, von Seidlein, Lorenz
core +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Pelayanan Kesehatan Gratis Untuk Warga Lanjut Usia Di Desa Kurahan
Jurnal Nuansa AkademikThis community service activity was carried out in Kurahan Village, Sidoarum Village, Godean District, Sleman Regency, with a focus on the elderly with an age range of 40 to 70 years who are a vulnerable group that often faces various chronic health ...
Viviane Annisa +9 more
doaj +1 more source
NORADRENALINE CONTENT IN THE HEART AND SPLEEN OF THE MOUSE UNDER NORMAL CONDITIONS AND AFTER ADMINISTRATION OF SOME DRUGS [PDF]
, 1962 D.F. Sharman +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Increased Response Variability and Attentional Lapses After Chronic Cocaine Self-Administration [PDF]
, 2009 In humans, cocaine use has long been associated with poor attentional control and decreased efficiency in goal-oriented behavior. Animal models of these stereotypic drug effects, however, have thus far failed to produce quantifiable data sets in part ...
Olsen, Adam
core
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source