Results 241 to 250 of about 7,897,516 (385)

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Studies on Metabolism of Drugs. IX. On the Excreted Substances in the Human Urine after Oral Administration of Sulfamethomidine

, 1968
Michihiro Ueda, Norihiko Murakami, KAZUKO FURUKI, Harumi Atsumura   +3 more
openalex   +2 more sources

Postmarket Safety Events Among Novel Therapeutics Approved by the US Food and Drug Administration Between 2001 and 2010

Journal of the American Medical Association (JAMA), 2017
Nicholas Downing, N. Shah, J. Aminawung, Alison M. Pease, J. Zeitoun, H. Krumholz, J. Ross   +6 more
semanticscholar   +1 more source

Mass drug administration coverage and its determinants for the elimination of onchocerciasis in Ulanga District, Tanzania. [PDF]

PLoS Negl Trop Dis
Mhiche AK, Gasarasi D, Kabona G, Hussein A, Mwingira UJ, Abade AM.   +5 more
europepmc   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Studies on the Methods of Control and of Administration of Drugs for Anticoagulant Therapy : Symposium on Heart Diseases and Anticoagulants

, 1963
Manabu D. Yamanaka
openalex   +2 more sources

ORAL DRUG SELF‐ADMINISTRATION IN RHESUS MONKEYS: INTERACTIONS BETWEEN DRUG AMOUNT AND FIXED‐RATIO SIZE [PDF]

, 1985
Gregory A. Lemaire, Richard A. Meisch
openalex   +1 more source

Exploring the impact of mobile and migrant populations on mass drug administration coverage and effectiveness in Africa: A scoping review protocol. [PDF]

PLoS One
Sangare M, Coulibaly YI, Ravichandran P, Diabate AF, Duguay C, Vlassoff C, Kulkarni MA, Krentel A.   +7 more
europepmc   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Anti-tuberculous Drug Administration for Non-treated Silicotuberculosis in Small Pottery Industries

, 1965
Shingo Shima, Y. Itakura
openalex   +2 more sources